Monoclonal Antibodies: Cytokines and Arthritis, Mediators of Inflammation and Therapy

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CRC Press, Mar 29, 1991 - Medical - 512 pages
Presents a sampling of new and novel approaches to the amelioration of musculoskeletal disease pathology, emphasizing prevention and therapy. Where applicable, these new technologies are focused on their application to human autoimmune diseases, but the volume mainly discusses and details the use of
 

Contents

New Horizons in the Treatment
1
Therapeutic Application of Monoclonal Antibodies in
11
Clinical Trial Design and Concepts for Biologic Agents in
23
Treatment of Patients with Rheumatoid Arthritis with
37
Human Monoclonal Autoantibodies
57
Concepts from
75
Cellular and Molecular Interactions in the Induction
101
Interleukin1 Inhibitors and Their Significance in Rheumatoid
133
A Mycobacterial 65 kd HeatShock Protein and T Cells
253
Immunotherapy of CollagenInduced Arthritis with AntiIa
269
AntiL3T4 Antibody Therapy in Systemic Lupus
289
Autoreactive B Cells in CollagenInduced Arthritis
313
Antiproteoglycan Antibodies in Experimental Spondylarthritis
341
Reproduction and Regulation of the Autoimmunity That
357
Serum Keratan Sulfate Concentration as a Measure of
373
CrossReactive Idiotypes of Rheumatoid Factors in Arthritis
399

Interleukins and Metalloproteinases in Arthritis
173
T Cell Cytokines as Immunomodulators of Arthritis Disease
199
Induction and Regulation of Arthritis by T CellDerived
225
Importance of T Cells and Antigen
237
Characterization of Rheumatoid Factors Using Monoclonal
413
The Human AntiDNA Idiotype 166 Idiotype
435
Immunoregulation in Systemic Lupus Erythematosus
465
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