Lewin's Genes Twelve

Jocelyn E. Krebs, Elliott S. Goldstein, Stephen T. Kilpatrick

Jones & Bartlett Learning, 2018 - Medical - 837 pages

Part 1 Genes and Chromosomes Chapter 1 Genes Are DNA and Encode RNAs and Polypeptides Chapter 2 Methods in Molecular Biology and Genetic Engineering Chapter 3 The Interrupted Gene Chapter 4 The Content of the Genome Chapter 5 Genome Sequences and Evolution Chapter 6 Clusters and Repeats Chapter 7 Chromosomes Chapter 8 Chromatin Part 2 DNA Replication and Recombination Chapter 9 Replication Is Connected to the Cell Cycle Chapter 10 The Replicon: Initiation of Replication Chapter 11 DNA Replication Chapter 12 Extrachromosomal Replicons Chapter 13 Homologous and Site-Specific Recombination Chapter 14 Repair Systems Chapter 15 Transposable Elements and Retroviruses Chapter 16 Somatic DNA Recombination and Hypermutation in the Immune System Part 3 Transcription and Posttranscriptional Mechanisms Chapter 17 Prokaryotic Transcription Chapter 18 Eukaryotic Transcription Chapter 19 RNA Splicing and Processing Chapter 20 mRNA Stability and Localization Chapter 21 Catalytic RNA Chapter 22 Translation Chapter 23 Using the Genetic Code Part 4 Gene Regulation Chapter 24 The Operon Chapter 25 Phage Strategies Chapter 26 Eukaryotic Transcription Regulation Chapter 27 Epigenetics I Chapter 28 Epigenetics II Chapter 29 Noncoding RNA Chapter 30 Regulatory RNA.

Contents

• DNA Replication and Recombination: 227
• Transcription and Posttranscriptional Mechanisms: 441
• Gene Regulation: 647
• Glossary: 783
• Index: 809

About the author

Jocelyn E. Krebs received a B.A. in Biology from Bard College, Annandale-on-Hudson, New York, and a Ph.D. in Molecular and Cell Biology from the University of California, Berkeley. For her Ph.D. thesis, she studied the roles of DNA topology and insulator elements in transcriptional regulation. She performed her postdoctoral training as an American Cancer Society Fellow at the University of Massachusetts Medical School in the laboratory of Dr. Craig Peterson, where she focused on the roles of histone acetylation and chromatin remodeling in transcription. In 2000, Dr. Krebs joined the faculty in the Department of Biological Sciences at the University of Alaska, Anchorage, where she is now a Full Professor. Her most recent research focus has been on the role of the Williams syndrome transcription factor (one of the genes lost in the human neurodevelopmental syndrome Williams syndrome) in early embryonic development in the frog Xenopus. She teaches courses in introductory biology, genetics, and molecular biology for undergraduates, graduate students, and first-year medical students. She also teaches courses on the molecular biology of cancer and epigenetics. Although working in Anchorage, she lives in Portland, Oregon, with her wife and two sons, a dog, and three cats. Her nonwork passions include hiking, gardening, and fused glass work.' Elliott S. Goldstein earned his B.S. in Biology from the University of Hartford in Connecticut and his Ph.D. in Genetics from the University of Minnesota, Department of Genetics and Cell Biology. Following this, he was awarded an NIH Postdoctoral Fellowship to work with Dr. Sheldon Penman at the Massachusetts Institute of Technology. After leaving Boston, he joined the faculty at Arizona State University in Tempe, Arizona, where he is an Associate Professor, Emeritus, in the Cellular, Molecular, and Biosciences program in the School of Life Sciences and in the Honors Disciplinary Program. His research interests are in the area of molecular and developmental genetics of early embryogenesis in Drosophila melanogaster. In recent years, he has focused on the Drosophila counterparts of the human protooncogenes jun and fos. His primary teaching responsibilities are in the undergraduate general genetics course as well as the graduate-level molecular genetics course. Dr. Goldstein lives in Tempe with his wife, his high school sweetheart. They have three children and two grandchildren. He is a bookworm who loves reading as well as underwater photography. His pictures can be found at http://www.public.asu.edu/~elliotg/. Stephen T. Kilpatrick received a B.S. in Biology from Eastern College (now Eastern University) in St. Davids, Pennsylvania, and a Ph.D. from the Program in Ecology and Evolutionary Biology at Brown University. His thesis research was an investigation of the population genetics of interactions between the mitochondrial and nuclear genomes of Drosophila melanogaster. Since 1995, Dr. Kilpatrick has taught at the University of Pittsburgh at Johnstown in Johnstown, Pennsylvania, where he is currently chair of the Department of Biology. His regular teaching duties include undergraduate courses in introductory biology for biology majors and advanced undergraduate courses in genetics (for both majors and nursing students), evolution, and molecular genetics. He has also supervised a number of undergraduate research projects in evolutionary genetics. Dr. Kilpatrick's major professional focus has been in biology education. He has participated in the development and authoring of ancillary materials for several introductory biology, genetics, and molecular genetics texts and online educational review sites as well as writing articles for educational reference publications. For his classes at Pitt-Johnstown, Dr. Kilpatrick has developed many active learning exercises in introductory biology, genetics, and evolution. Dr. Kilpatrick resides in Johnstown with his wife and four cats. Outside of scientific interests, he enjoys music, literature, and theater.

Bibliographic information

• Title: Lewin's Genes Twelve; Volume 500 of Lewin's Genes XII, Stephen T. Kilpatrick
• Authors: Jocelyn E. Krebs, Elliott S. Goldstein, Stephen T. Kilpatrick
• Editors: Jocelyn E. Krebs, Elliott S. Goldstein, Stephen T. Kilpatrick
• Edition: illustrated, reprint
• Publisher: Jones & Bartlett Learning, 2018
• ISBN: 1284104494, 9781284104493
• Length: 837 pages
• Subjects: Medical / Physician & Patient (incl. Narrative Medicine); Science / Life Sciences / Biology; Science / Life Sciences / Evolution; Science / Life Sciences / General; Science / Life Sciences / Genetics & Genomics; Science / Life Sciences / Molecular Biology