Modelling Methodology for Physiology and Medicine
Ewart Carson, Claudio Cobelli
Elsevier, Dec 31, 2000 - Technology & Engineering - 421 pages
Modelling Methodology for Physiology and Medicine offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modelling methodology that is widely applicable to physiology and medicine. The book opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration.
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Chapter 4 A priori Identifiability of Physiological Parametric Models
Chapter 5 Parameter Estimation
Chapter 6 Tracer Experiment Design for Metabolic Fluxes Estimation in Steady and Nonsteady State
Chapter 7 Physiological Modelling of Positron Emission Tomography Images
Chapter 8 Identification and Physiological Interpretation of Aortic Impedance in Modelling
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accessible pool airway algorithm alveoli analysis aortic Appl Physiol approach assessment assumed basal Bayesian Bayesian networks Biomed Biomed Eng blood flow blood-tissue exchange body-end Buchberger algorithm Burattini C-peptide calculated capillary Carson Caumo characteristic clamp clinical Cobelli compartment compartmental models complex components Comput deconvolution derived described diabetes diffusion DiStefano III distribution dynamic equations exogenous experimental feedback FIFDG Figure FiO2 fluxes frequency function global identifiability glucose concentration glucose kinetics glucose production Gröbner basis heterogeneity impulse response input impedance insulin kinetics insulin secretion interstitial fluid IVGTT linear lung capillary Lutchen matrix measurement error method minimal model nonsteady obtained output oxygen Panel parameter estimation parameter vector patient perfusion physiological systems plasma polynomials positron emission tomography pressure priori problem pulmonary Ra(t regularisation respiratory system sampling shunt simulation solution steady structure technique time-varying tion tissue tracer tracer infusion tracer-to-tracee ratio unknown variables viscoelastic Westerhof Windkessel
Page 398 - Crone, C. , The permeability of capillaries in various organs as determined by use of the 'indicator diffusion