Decoding Darkness: The Search For The Genetic Causes Of Alzheimer's Disease
Working from the intriguing hypothesis that Alzheimer's dementia is the result of a renegade protein-beta amyloid-Tanzi and others set out to find the gene responsible for its production. Decoding Darkness takes us deep into the minds and far-flung labs of many a prominent researcher, offering an intimate view of the high stakes of molecular genetics, the revolution that propels it, the obstacles that threaten to derail it, and the families whose lives are so dependent upon it. Tanzi and Parson ultimately reveal that Alzheimer's, like heart disease, may be effectively treated-even prevented.
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Decoding darkness: the search for the genetic causes of Alzheimer's diseaseUser Review - Not Available - Book Verdict
Following Daniel Pollen's Hannah's Heirs (LJ 6/93; updated in 1996), this engrossing book is the second major account of the race to uncover the genetics behind Alzheimer's disease as told by one of ... Read full review
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A-beta A-beta peptide aggregation Alzheimer Disease Alzheimer families Alzheimer mutation Alzheimer patients Alzheimer research Alzheimer's amyloid amyloid gene amyloid plaques amyloid protein amyloidosis APOE APP gene APP protein APP's Athena Athena Neurosciences beta biotech blood brain tissue Broeckhoven cause cells cerebral Christine Van Broeckhoven chromo chromosome 21 compounds cortex defect dementia Dennis Selkoe disease gene disease's disorder drug early enzymes Familial Alzheimer's Disease fibrils field finding gamma-secretase GenBank gene on chromosome gene's genetic geneticist George Glenner Glenner Goldgaber Gusella Gusella's lab Huntington's Hyslop inherited isolated Jim Gusella John Hardy lab's late late-onset linkage markers Mass General's Moir molecular mouse Mullan mutation neurons Neuroscience Neve Noonan normal older paper pathology peptide percent plaques and tangles presenilin probes protease inhibitor region Robert Schellenberg Science scientists secretases sequence SIBIA studies syndrome tion toxic transgenic mice University Volga German Wasco Yankner