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Some Aspects on Distribution and Role of Opioid Peptides in the Central
Some Aspects of StructureFunction Relationship
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A. R. Genazzani Acad acid ACTH action activity addicts administration agonists analgesia analgesic analog animals antagonist B-endorphin B-EP and B-LPH basal behavior Biochem Brain Res cells Clin Clinical Aspects concentrations DADLE decrease dermorphin dopamine doses drugs dynorphin E. E. Muller edited by E. E. effect Endocrinol Endocrinology endogenous opioid endorphins enkephalin function ganglionic glucose haloperidol Hokfelt Holaday hormone hypothalamus immunoreactive increase induced inhibition injection intake Italy Kastin leumorphin ligands mediated Met-enkephalin mg/kg mice Milan morphine mRNA naloxone naltrexone Natl neurons Neurosci ng/rat nucleus observed opiate receptors opioid peptides opioid receptors patients peripheral Pharmacol Pharmacology pituitary plasma plasma levels POMC potent precursor pro-enkephalin Proc proopiomelanocortin radioimmunoassay rats Raven Press release response rimorphin role saline secretion significant significantly specific stimulation studies suggested tested tissue University University of Milan vitro vivo