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AAV DNA AAV genome adeno-associated virus adeno-associated virus AAV adenovirus antigen base pair Bennington Bethesda Cancer capsids coinfected complementary strands contain defective DENSONUCLEOSIS VIRUS Department of Molecular DNA molecules DNA polymerase DNA polymerase activity DNA replication DNA synthesis double-stranded duplex electron microscopy encapsidation exonuclease fibroblast fragments g/cc GAUTSCHI gel electrophoresis genome gradients hairpin hamsters helper Hygiene and Medical Institute for Medical Institute of Hygiene Institutes of Health James Cook University KB cells Kilham rat virus label Laboratory maps maturation Medical Microbiology Medical Research minute virus Molecular Biophysics molecular weight monomer National Institutes nuclease nuclei nucleotide Oak Ridge particles banding PARVOVIRUS LuIII peptides polypeptides porcine parvovirus progeny proteins Putnam Memorial Hospital replicative form RF DNA S. L. Rhode sedimentation sequences SIEGL single-stranded structural proteins studies susceptible template University of Berne viral DNA viral proteins virion DNA virions virus particles viruses vitro vivo wt H-l