Magnetic Resonance Imaging: Physical Principles and Sequence Design

Front Cover
New edition explores contemporary MRI principles and practices

Thoroughly revised, updated and expanded, the second edition of Magnetic Resonance Imaging: Physical Principles and Sequence Design remains the preeminent text in its field. Using consistent nomenclature and mathematical notations throughout all the chapters, this new edition carefully explains the physical principles of magnetic resonance imaging design and implementation. In addition, detailed figures and MR images enable readers to better grasp core concepts, methods, and applications.

Magnetic Resonance Imaging, Second Edition begins with an introduction to fundamental principles, with coverage of magnetization, relaxation, quantum mechanics, signal detection and acquisition, Fourier imaging, image reconstruction, contrast, signal, and noise. The second part of the text explores MRI methods and applications, including fast imaging, water-fat separation, steady state gradient echo imaging, echo planar imaging, diffusion-weighted imaging, and induced magnetism. Lastly, the text discusses important hardware issues and parallel imaging.

Readers familiar with the first edition will find much new material, including:

  • New chapter dedicated to parallel imaging
  • New sections examining off-resonance excitation principles, contrast optimization in fast steady-state incoherent imaging, and efficient lower-dimension analogues for discrete Fourier transforms in echo planar imaging applications
  • Enhanced sections pertaining to Fourier transforms, filter effects on image resolution, and Bloch equation solutions when both rf pulse and slice select gradient fields are present
  • Valuable improvements throughout with respect to equations, formulas, and text
  • New and updated problems to test further the readers' grasp of core concepts

Three appendices at the end of the text offer review material for basic electromagnetism and statistics as well as a list of acquisition parameters for the images in the book.

Acclaimed by both students and instructors, the second edition of Magnetic Resonance Imaging offers the most comprehensive and approachable introduction to the physics and the applications of magnetic resonance imaging.


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Title page
Foreword to the First Edition
Magnetic Resonance Imaging
Classical Response of a Single Nucleus to
Rotating Reference Frames and Resonance
Magnetization Relaxation and the Bloch
Transform Shift Concepts and Point Spread
Projection Reconstruction of Images
Signal Contrast and Noise
A Closer Look at Radiofrequency Pulses
WaterFat Separation Techniques
Fast Imaging in the Steady State
Segmented kSpace and Echo Planar
Magnetic Field Inhomogeneity Effects

The Quantum Mechanical Basis of Precession
The Quantum Mechanical Basis of Thermal
Signal Detection Concepts
Introductory Signal Acquisition Methods
OneDimensional Fourier Imaging kSpace
Chapter 10
MultiDimensional Fourier Imaging
Chapter 11
The Continuous and Discrete Fourier
Fourier transform pairs which
Properties of D the discrete Fourier
Sampling and Aliasing in Image
Filtering and Resolution in Fourier
for Random Susceptibility
Random Walks Relaxation and Diffusion
Spin Density T1 and T2 Quantification
Motion Artifacts and Flow Compensation
MRAngiography and Flow Quantification
Magnetic Properties of Tissues
Sequence Design Artifacts
Introduction to MRI Coils and Magnets
Parallel Imaging
Electromagnetic Principles
End User License Agreement

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About the author (2014)

Robert W. Brown, Ph.D.
Institute Professor and Distinguished University Professor
Case Western Reserve University, Cleveland, Ohio, USA
His research group efforts have resulted in over 200 published papers and abstracts, and his former students hold at least 150 patents (eight co-authored by him) and he has done important work in radiation physics, MRI, PET, CT, electromagnetics, inverse methods, mechanical and thermal modeling, nonlinear dynamics, EEG, MEG, sensors, and physics education, as well as a professional-life-long involvement in elementary particle physics and cosmology.

Yu-Chung N. Cheng, Ph.D.
Associate Professor of Radiology
Wayne State University, Detroit, Michigan, USA

E. Mark Haacke, Ph.D.
Professor of Radiology, Wayne State University, Detroit, Michigan, USA
Professor of Physics, Case Western Reserve University, Cleveland, Ohio, USA
Adjunct Professor of Radiology, Loma Linda University, Loma Linda, California, USA
Adjunct Professor of Radiology, McMaster University, Hamilton, Ontario, Canada
Distinguished Foreign Professor, Northeastern University, Shenyang, Liaoning, China
Director of The Magnetic Resonance Imaging Institute for Biomedical Research and Professor of Radiology, Department of Biomedical Engineering, Wayne State University. Dr. Haacke has two decades of experience teaching courses in physics, mathematics and statistics.

Michael R. Thompson, Ph.D.
Principal Scientist, Toshiba Medical Research Institute,
Cleveland, Ohio, USA

Ramesh Venkatesan, D.Sc.
Manager, MR Applications Engineering
Wipro GE Healthcare Pvt. Ltd., Bangalore, Karnataka, India

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