Materials and Strategies for Lab-on-a-Chip - Biological Analysis, Cell-Material Interfaces and Fluidic Assembly of Nanostructures: Volume 1191

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Sashi K. Murthy, Saif A. Khan, Victor M. Ugaz, Henry C. Zeringue
Cambridge University Press, Nov 12, 2009 - Technology & Engineering - 149 pages
The development of miniaturized systems for chemical and biochemical analysis has grown to the point where lab-on-a-chip devices are now important enabling tools in a diverse array of application areas. As the size of these systems continues to shrink, details of the micro- and nanoscale phenomena associated with their construction and operation must be considered. This book focuses on materials and engineering aspects of lab-on-a-chip devices and the application of microfluidics to materials synthesis. A microfabricated fluidic system integrating biological sample treatment and detection on a single chip offers the promise of low-cost, rapid and high-performance analysis. These devices can perform high-throughput biochemical assays for drug discovery and provide portability for point-of-care diagnostics and biothreat monitoring. Topics include: frontiers in lab-on-a-chip research; materials for lab-on-a-chip; materials synthesis on chip; cell manipulation and biomimetics on chip; porous materials in lab-on-a-chip; sensing and detection on chip - molecular level; sensing and detecting on chip - cells and particles; and sensing and detection on chip - DNA.

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Contents

ScreenGrid Field Effect Transistor for Sensing
127
Resonant Microcavities Coupled to a Photonic
133
PhosphateDependent DNA Immobilization
141
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