Hereditary Colorectal Cancer: Proceedings of the Fourth International Symposium on Colorectal Cancer (ISCC-4), November 9-11, 1989, Kobe, Japan
This book provides comprehensive and multidisciplinary coverage of colorectal cancer genetics. It captures the active thinking of many of the most noteworthy investigators on this subject, with more than 70 contributors presenting research from around the world. The topics include genetic heterogeneity, pathology, hereditary colorectal cancer syndrome classification, biomarker research, screening strategies, and the registration of cancer-prone families. This is a timely publication which provides an eclectic approach to the entire field of colorectal cancer genetics.
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The Concept of Hereditary Colorectal Cancer
Historical and Natural Cancer History Facets of the Lynch
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abnormalities activity adenocarcinoma adenomas adenomatous polyps allele allele loss analysis antigen associated biopsy Bodmer Bussey calcium cancer family syndrome Cancer Res carcinogenesis cell lines cellular chemoprevention chromosome clinical colectomy colon cancer colon carcinoma colon tumors colonic mucosa colonoscopy colorectal cancer colorectal carcinomas crypt deletion detected diagnosis diet dietary disease effect endometrial endometrial cancer epithelial cell epithelium examination expression extracolonic familial adenomatous polyposis familial polyposis familial polyposis coli family history FAP patients fiber flat adenomas frequency Gardner's syndrome gastric gastrointestinal high risk histologic HNPCC human colorectal increased inherited intestinal juvenile polyposis labeling index lesions linkage Lipkin Lynch HT Lynch syndrome malignant markers molecular mucosa multiple mutations Nakamura neoplasia neoplastic nonpolyposis colorectal cancer observed oncogene Ornithine Decarboxylase patients with familial pedigree phenotype piroxicam polyamine proliferation ras gene rats rectal rectum reported screening sigmoidoscopy sporadic surveillance Table tissue treatment Utsunomiya Vogelstein