Bioseparations: downstream processing for biotechnology
Offers a concise introduction to the separation and purification of biochemicals. Bridges two scientific cultures, providing an introduction to bioseparations for scientists with no background in engineering and for engineers with little grounding in biology. The authors supplement the ideas by simple worked examples, making the techniques of bioseparations easy to learn. Discusses removal of insolubles, product isolation, purification and polishing.
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Filtration and Microfiltration
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adsorbent adsorption amino acids amyl acetate analysis antibiotic aspartame basic batch beer biological biomass bioseparations broth cake calculate cell centrifuge cephalosporin chapter chemical potential chromatography column containing crystals denaturation density described detergents diameter dilute solution disc discussed dryer drying electrophoresis elution chromatography enzyme equation equilibrium equipment estimate example feed fermentation filter aid filtration fixed bed flow g/liter given heat humidity initial insolubles isoelectric isoelectric point isotherm laboratory large scale linear liquid liters liters/hr mass balance materials membrane method microfiltration microorganisms molecular weight molecules nltration nucleation number of stages operations osmotic pressure packed packed bed particles precipitation pressure drop protein purification purity rate constant removed resin result rupture salt scale-up Section separation shown in Figure solids solubility solute concentration solvent standard deviation stigmasterol Table tank temperature tion tube ultrafiltration vapor velocity viscosity volume yield