The Secretory Immune System

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This report is the proceedings of a conference entitled The Secretory Immune System held May 4-7, 1982. The first session of the conference dealt with environmental influences on the induction of the IgA response. This includes regulation of B-cells for IgA genes, and lymphoreticular cell types present in IgA-inductive sites. The second session focused on the important observation that oral administration of antigen can simultaneously lead to IgA responses in secretions and systemic unresponsiveness or oral tolerance. The third session focused more closely on regulatory aspects of cells engaged in the IgA response. These studies include discussion of the IgA-rheumatoid factor and the role of IgE in muscosal immunity. Aging and mucosal immunity also receives emphasis. The fourth session largely focused on recent aspects of transport of IgA and IgA-immune complexes by the liver. The fifth session was devoted entirely to IgA immunity and immune dysfunctions in man. The sixth session was devoted entirely to effective functions of IgA.

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Contents

Inductive Aspects Regulatory Cells and Effector
48
Binding of Bacterial Lipopolysaccharide to Murine Lymphocytes By D M
72
Development of Immunological Capacity under Germfree
96
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