Sustained and Controlled Release Drug Delivery SystemsJoseph R. Robinson |
Contents
Terminology and Literature | 3 |
Conclusions | 48 |
DRUG PROPERTIES INFLUENCING THE DESIGN | 71 |
Copyright | |
30 other sections not shown
Common terms and phrases
absorption acetate acid action dosage forms activity administration agents Amer amount of drug Antibiot aqueous bioavailability biological blood level body CH3 CH3 chemical Clin clinical coating controlled release derivatives diffusion dissolution dosage form drug concentration drug delivery drug delivery system drug level drug molecules drug release duration effect esters estradiol ethynodiol diacetate evaluation excretion Figure fluid formulation hydrolysis implantation insulin intramuscular injection intravenous kinetics long-acting matrix matrix-type membrane metabolism metabolite muscle nandrolone norgestomet oral parenteral particles partition coefficient patients penicillin permission from Ref Pharm pharmacokinetic Pharmacol pilocarpine plasma polymer polymeric device procainamide prodrug progesterone quinidine rabbit rate constant rats release drug release of drug release rate Reproduced with permission serum silicone capsules solubility solution steroid studies subcutaneous sustained release sustained release product sustained-release Table tablet testosterone theophylline Ther therapy tion tissue tmax toxicity U.S. Patent values vitro vivo zero-order