Human papillomavirus and cervical cancer
International Agency for Research on Cancer, 1989 - Medical - 155 pages
This volume reviews the evidence for a causal link between sexually transmitted infection with human papillomavirus (HPV) and the occurrence of cervical cancer, from a variety of different angles. Epidemiological studies and clinical, pathological, and cytological aspects of HPV infection are reviewed. Modern methods for analyzing HPV-DNA types by molecular biological techniques are described, and the statistical problems to be overcome in epidemiological work are explained. The volume was prepared by a broad team of experts from around the world, who met in Copenhagen in March 1988 to reach a consensus on the present state of understanding and to establish directions for future work.
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Epidemiology of cervical cancer
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abnormal assessment association atypia biopsy Campion CARCINOGENS case-control study cellular cervical carcinoma cervical HPV infection cervical intraepithelial neoplasia cervical neoplasia cervical smears cervicography clinical cohort studies colposcopic condylomata acuminata controls cytological diagnosis DNA hybridization dot blot dysplasia Edited epidemiological epidemiological studies epithelial epithelium evidence exposure flat HPV lesions genital tract genital warts Gissmann Gynecol Hausen histological HPV DNA HPV infection HPV sequences HPV types human papillomavirus human papillomavirus infection human papillomavirus type immunosuppression increased risk intercourse invasive cancer invasive cervical cancer Lorincz Meisels membrane morphological neoplastic normal nucleic acid number of sexual Obstet oral contraceptives Pap smear papilloma papillomavirus DNA patients population prevalence of HPV probes reported Research on Cancer risk factors sample Schneider screening sexual partners sexually transmitted diseases significant smoking Southern blot specimens technique tissue transformation tumour type 16 type-specific uterine cervix variables viral DNA viral genome virus type Volume women