Design Principles for the Immune System and Other Distributed Autonomous Systems
Lee A. Segel, Irun R. Cohen
Oxford University Press, Jun 14, 2001 - Computers - 428 pages
Design Principles for the Immune System and Other Distributed Autonomous Systems is the first book to examine the inner workings of such a variety of distributed autonomous systems--from insect colonies to high level computer programs to the immune system. It offers insight into the fascinating world of these systems that emerge from the interactions of seemingly autonomous components and brings us up-to-date on the state of research in these areas. Using the immune system and certain aspects of its functions as a primary model, this book examines many of the most interesting and troubling questions posed by complex systems. How do systems choose the right set of agents to perform appropriate actions with appropriate intensities at appropriate times? How in the immune system, ant colonies and metabolic networks does the diffusion and binding of a large variety of chemicals to their receptors permit coordination of system action? What advantages drive the various systems to complexity, and by what mechanisms do the systems cope with the tendency toward unwieldiness and randomness of large complex systems?
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New Approaches to Complex Chemical Reaction
Control Mechanisms for Distributed Autonomous
Task Allocation in Ant Colonies
Biologically Motivated Distributed Designs for Adaptive
Analogy Making as a Complex Adaptive System
Immunology as Information Processing
T Cells Obey the Tenets of Signal Detection Theory
Multistep Navigtation and the Combinatorial Control
Other editions - View all
Acad activated adaptive immune system affinity allograft anergy antibodies antigen apoptosis Arthritis autoimmune diseases binding biological CD4+ T Cells chemical chemoattractant chemokines clonal clones clonotypes complex costimulation cytokines dendritic cells detection detector diabetes different MHC molecules differentiation distributed effect effector endothelial cells epitopes evolved example Experimental Autoimmune expression feedback function genes genetic Golem H. L. Weiner host Human immune network immune response Immunol immunologic individual induce infection inflammation inflammatory information resources inhibit innate immune innate immune system integrins interactions Interleukin intracellular keywords leukocytes ligands lymphocytes lymphokine macrophages mechanisms mediated memory MHC diversity mice Monocytes multiple Myelin Myelin Basic Protein Natl Natural Killer Cell negative selection Oral Administration oral tolerance pathogens patterns peptides Peyer’s patches principle Proc production proliferation proteins receptorligand pairs receptors Regulation regulatory repertoire Role secretion signals specific stimulated structure studies Suppression task Tcell Th cells tissue Transplantation triggered types users vitro vivo