Prostate Biopsy Interpretation: An Illustrated Guide

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Springer Science & Business Media, Sep 29, 2011 - Medical - 185 pages

This book covers all the practical issues related to the interpretation of prostatic biopsies in day-to-day practice, including: biopsy sampling and processing; the diagnosis of limited cancer; differentiation of prostate cancers from benign lesions and recognition of histologic variants; the recognition and clinical significance of “atypical” diagnoses and HGPIN; the identification of recently described entities; the contemporary approach to Gleason grading; the utility of immunohistochemical markers and emerging molecular markers; and the reporting of prostate biopsies. Algorithms, flow charts, and tables are used throughout to simulate the thought and decision-making process upon encountering common clinical scenarios during sign-out of prostate biopsy. The book is richly illustrated with carefully selected, high-quality color images and will appeal especially to practicing surgical pathologists as well as pathology residents and fellows in training.

 

Contents

Anatomy and Normal Histology of the Prostate Pertinent to Biopsy Practice
1
Prostate Needle Biopsy Sampling Techniques Impact on Pathological Diagnosis
11
Diagnosis of Limited Cancer in Prostate Biopsy
15
Immunohistochemistry in Prostate Biopsy Evaluation
29
Contemporary Approach to Gleason Grading of Prostate Cancer
41
Histologic Variants of Prostate Carcinoma
56
Benign Mimics of Prostate Carcinoma
79
Atypical Cribriform Lesions of the Prostate Gland Emerging Concepts of Intraductal Carcinoma of the Prostate IDCP
115
Atypical Glands Suspicious for Cancer
131
Spindle Cell Lesions of the Prostate Gland
139
Treatment Effect in Benign and Malignant Prostate Tissue
146
Molecular Biology of Prostate Cancer and Emerging Diagnostic and Prognostic Biomarkers
157
Biopsy Specimen Handling Processing Quality Assurance Program
168
Reporting of Prostate Biopsy
173
Index
181
Copyright

HighGrade Prostatic Intraepithelial Neoplasia
121

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