Bacterial Adherence, Volume 6, Part 2Edwin H. Beachey Bacteria adhere to and colonize almost any surface. Within minutes after sub merging a solid object in seawater or freshwater, the surface becomes colonized by adherent micro-organisms, and the earliest organisms to adhere are bacteria. Adherent colonies of bacteria have also been observed on particles of sand, soil, other bacteria, plant tissues, and a variety of animal tissues. Shortly after birth, the skin and the mucosal surfaces of the upper respiratory tract and the gastro intestinal tract of animals and man become heavily colonized by a variety of adherent bacteria which persist in varying numbers as indigenous parasites. The apparent symbiotic balance between the host and his indigenous parasites oc casionally is upset by the invasion of harmful bacteria which adhere to and colonize these surfaces. Pathogenic bacteria may also adhere to and colonize normally sterile surfaces such as the mucosa of the genito-urinary tract and the lower respiratory tract, and occasionally even endothelial surfaces of the cardiovascular system, resulting in the development of serious infectious diseases. Although marine microbiologists have been aware for a long time that bacteria must stick to surfaces in order to avoid being swept away by moving streams of water, not until recently has it been widely recognized that adherence must be an important ecological determinant in the colonization of specific sites in plants and animals, and in particular an important early event in the pathogenesis of bacterial infections in animals and man. It is true that Dr G. |
Contents
2 | 33 |
4 | 53 |
Adherence of Normal Flora to Mucosal Surfaces 31 | 57 |
Copyright | |
18 other sections not shown
Other editions - View all
Common terms and phrases
activity adhesin adhesive properties adsorbed adsorption agglutination aggregation animal antibodies antigen associated attachment Bact bacteria bacterial adherence bacterial attachment Beachey binding Brinton broth buccal cells carbohydrate Caries cell surface cholera vibrios cholerae coli colonization components culture D-mannose dental Dental Caries dental plaque dextran Duguid and Gillies electron microscopy enzyme epithelial cells epithelial surfaces epithelium erythrocytes Evans extracellular filamentous fimbriae fimbriated gonococci Freter gastro-intestinal Gibbons glucan glycoproteins GTase guinea pig haemagglutinating haemagglutinins Hamada host cell Houte human hydrophobic hydroxyapatite Immun Infect inhibited interactions intestine isolated Jones lectin ligand lipoteichoic acid mechanisms micro-organisms Microbiol molecules motility MR/K MRE adhesins mucosal surfaces mucus mutans cells mycoplasma Neisseria non-fimbriated Ofek oral Biol organisms Ørskov pathogenic pellicle plaque platelets pneumoniae polymers polysaccharides present protein receptor red cells saliva salivary sanguis Savage serotype Slade species strains Strep streptococci studies sucrose suggested synthesis Table teeth tissue type-1 fimbriae vibrios vitro vivo Wicken