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5-methyl tetrahydrofolate absorption adolescents alcoholics anticonvulsants bioavailability biochemical blood bone marrow Botez Butterworth casei assay cell folate levels Chanarin ciency Clin clinical Colman compromised folate status correlate deoxyuridine determination diet dietary folate dietary intakes elderly folacin folate content folate deficiency folate intake folate metabolism folate values folates in foods folic acid deficiency food folate food fortification formiminoglutamic acid glutamate groups Haematol Halsted Health hematologic hemoglobin Herbert hypersegmentation intestinal Krumdieck Lactobacillus casei low serum lymphocytes maize maize meal malabsorption megaloblastic anemia metabolism method Metz microbiological assay monoglutamates National Research Council neutrophils ng/ml Nutr Nutrition Board nutrition surveys oral patients pernicious anemia plasma polyglutamates population pregnant women radioassay radiometric binding assay red cell folate reported risk of folate Rosenberg samples Sauberlich SCIENCES RESEARCH OFFICE serum and red Stokstad studies sulfasalazine suppression test Tamura tetrahydrofolIc acid total folate U.S. Department U.S. Government Printing Waxman yg/d