Heart Hypertrophy and Failure
Naranjan S. Dhalla, Grant N. Pierce, Vincenzo Panagia, Robert E. Beamish
Springer, Dec 31, 1995 - Medical - 531 pages
Heart Hypertrophy and Failure brings together leading basic scientists and clinicians, presenting improved knowledge of the pathophysiology and treatment of the condition. The result is a synthesis of state-of-the-art information on molecular biology, cellular physiology and structure-function relationships in the cardiovascular system in health and disease. The papers presented describe fundamental mechanisms underlying changes in the cellular machinery during the development of cardiac hypertrophy and heart failure.
Audience: Students, scientists, clinical and experimental cardiologists who seek to understand and manage the perplexing problems of hypertrophy and heart failure.
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Molecular analysis of genotypephenotype correlations
Does decreased energy supply contribute to heart failure? The role of
Genetically determined cardiomyopathies in neuromuscular disease
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Acad Sci USA activity adenylyl cyclase agonists alterations angiotensin ATPase atrial Biochem Biol Chem BMHC c-myc Ca"-ATPase calcium cardiac growth cardiac hypertrophy cardiac muscle cardiac myocytes cardiomyocytes cDNA cellular chromosome Circ Res Clin Invest clones collagen congestive heart failure contractile decreased deletion diabetic diastolic dilated cardiomyopathy disease dystrophin effects enalapril failing hearts failing human heart familial hypertrophic fetal Figure function G-protein gene expression genetic hamster heart rate hypertensive hyperthyroid hypertrophic cardiomyopathy increased induced intracellular isoform isoproterenol left ventricle left ventricular LVFW MacLennan DH mechanisms membrane mitochondrial DNA Mol Cell Cardiol molecular mRNA mtDNA muscular dystrophy mutations myocardial infarction myocardium Natl Acad Sci nonfailing norepinephrine Northern blot nucleotide patients perfused phenotype phospholamban phosphorylation Physiol piglets pressure overload Proc Natl Acad protein kinase protein levels rabbit rat heart receptor regulation response role sarcoplasmic reticulum sequence stimulation studies synthesis thyroid hormone tissue transcription uptake ventricular myocytes