Pathophysiology of Heart Failure

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Naranjan S. Dhalla
Springer, Dec 31, 1995 - Medical - 578 pages
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Pathophysiology of Heart Failure brings together leading basic scientists and clinicians, presenting new approaches to this complex problem, involving cardiomyopathic processes and ischemia perfusion injury. The result is a synthesis of state-of-the-art information on molecular biology, cellular physiology and structure-function relationships in the cardiovascular system. The role which excess intracellular calcium plays in the genesis of cardiac dysfunction is described as a fundamental mechanism underlying heart failure; one which may lead to improved prevention and treatment.
Audience: Clinical and experimental cardiologists will find the book a helpful source of ideas and inspiration.

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Experimental models of heart failure and cardiomyopathy
Role of the slow sodium channel in hereditary cardiomyopathy
Changes in contractile proteins under oxidative stress

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