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Depolarising and Nondepolarising Muscle Relaxants and Dual Block
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acetyl acetylcholine action of curare activity administered affinity constant Anaesthesia anaesthetists Anesthesiology antagonist drug anticholinesterase binding block produced bradycardia British Journal calcium cause cell cent choline cholinesterase Churchill Davidson clinical Cohen concentration curare curare-like drugs curarisation d-tubocurarine decamethonium demonstrated depolarising depolarising agents depolarising drug depolarising relaxants dose of curare dual block duration of action edrophonium effect endplate evidence excretion extracellular Figure gallamine halothane hypotension increased injection ions Journal of Anaesthesia Journal of Pharmacology Journal of Physiology Katz liver metabolism methonium molecules motor nerve muscle relaxant drugs muscle relaxants muscular block myasthenia gravis myoneural junction neostigmine neuro neuromuscular block neuromuscular conduction neuromuscular transmission non-depolarising muscle relaxants non-depolarising relaxants normal observations occur pancuronium paralysis Paton Pharmacology Phase II block post-tetanic postsynaptic membrane potassium presynaptic prolonged pseudocholinesterase receptor substance recovery release of acetylcholine response result reversal sensitivity succinylcholine suggested suxamethonium synaptic cleft temperature tetanic stimulation tion volatile anaesthetic Waud Zaimis