Molecular Applications in Biological Anthropology
Eric J. Devor, Eric Jeffrey Devor
Cambridge University Press, Dec 17, 1992 - Science - 258 pages
The recent revolution in molecular genetics, which has already made such a significant impact in the biomedical sciences, is now becoming established in biological anthropology. New techniques have enabled anthropologists to study biological variation at the molecular level, and a wealth of exciting information on human and non-human primate populations is now becoming available for the first time. This volume presents a selection of pioneering research studies in which molecular techniques have been used to address key questions, for example about the human genetic system, the geographical movements of human populations in the past, and primate evolution. Providing not only a timely overview of current research, this book also presents an insight into the potential significance of molecular biology in the decades to come, that will be of interest to all biological anthropologists as well as molecular biologists, human geneticists, palaeontologists and evolutionary biologists.
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Academy of Sciences Acids African alleles American Journal analysis approach associated B-globin baboons base Biology Brown cell changes chromosome cloned common containing deletion detected determine distribution divergence DNA sequence effects estimate et al evidence evolution evolutionary examined example families fingerprinting four fragments frequencies genome globin gene groups haplotypes Human Genetics hybridization hypervariable individuals Italy Jeffreys Journal of Human known length levels loci locus macaques malaria male method minisatellite mitochondrial DNA molecular mtDNA mutations National Academy Nature nuclear nucleotide nucleotide sequence occurred origin patterns phylogenetic phylogeny polymorphisms Polynesians population genetic populations possible present Press primate probes Proceedings processes produced protein recent recombination region relationships relatively repeats Research restriction enzyme result RFLPs Sciences USA selection separated showed similar single species structure studies suggest thalassaemia types University variability variation Wilson World monkeys