Chiral Reagents for Asymmetric Synthesis, Volume 5Derived from the renowned, Encyclopedia of Reagents for Organic Synthesis (EROS), the related editors have created a new handbook which focuses on chiral reagents used in asymmetric synthesis and is designed for the chemist at the bench. This new handbook follows the same format as the Encyclopedia, including an introduction and an alphabetical arrangement of the reagents. As chiral reagents are the key for the successful asymmetric synthesis, choosing the right reagents is essential, in this handy reference the editors give details on how to prepare, store and use the reagents as well as providing key reactions to demonstrate where reagents have been successfully used.
All reagents included will be added to e-EROS – please visit the site where you can gain access to over 50,000 reactions and 3,800 of the most frequently consulted reagents. Visit: www.interscience.wiley.com/eros |
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Contents
Ely Lactale iij ſitAſſiſſilſ | 1 |
Organic Synthesis Procedures Featuring Chiral | 7 |
tButyl 2tButyl3methyl4oxo1imidazolidine | 9 |
SAcetocarbonylcyclopentadienyltriphenyl | 21 |
1R2S1Amino23dihydro1Hinden2ol | 27 |
2Amino3methyl11diphenyl1butanol | 36 |
LAspartic Acid | 42 |
1R5R2H15Benzodithiepin34Hone 15Dioxide | 48 |
Dihydroquinidine Acetate | 221 |
Diisopinocamphenylborane | 228 |
Glycidyl Tosylate 349 cyclopenten1one Ar246triisopropylphenyl | 425 |
2S20338aßHexahydro3hydroxymethyl8a BMethyl3propiolactone | 433 |
S2HydroxyNNdimethylpropanamideOO R+MethylpTolyl Sulfoxide | 439 |
Monoisopinocampheylborane | 445 |
NorephedrineBorane | 454 |
2S203ao40707ax233a45677aOctahydro | 462 |
R2tButyl6methyl4H13dioxin4one | 51 |
Benzylmethoxymethylmethylamine | 56 |
NBenzyloxycarbonylLserine BLactone | 68 |
1hepta25diene2S3Sbis | 74 |
1R1R2R2R11Bicyclopentyl22diylbis | 81 |
R11Bi22naphthotitanium Dichloride | 90 |
38 | 103 |
56 | 119 |
57 | 128 |
70 | 137 |
R+tButyl 2pTolylsulfinylacetate | 171 |
81 | 180 |
Camphorylsulfonyloxaziridine | 184 |
Chloromcyclopentadienyl4R trans22dimethyl | 190 |
R+Cyclohexyl2anisylmethylphosphine | 197 |
RR12Diamino12ditertbutylethane | 208 |
10Dicyclohexylsulfonamidoisoborneol | 214 |
tLeucine tButyl Ester 375 2R4R24Pentanediol | 468 |
8Phenylmenthyl Glyoxylate | 474 |
4S5S4Methoxymethyl2methyl5phenyl2 Pseudoephedrine | 485 |
Quinine | 498 |
1R5R6RSpiro44nonane16diyl | 504 |
Acid Ethyl Ester | 516 |
R+3pTolylsulfinylpropionic Acid 517 LTyrosine Hydrazide | 525 |
RR326Diisopropoxybenzoyloxy5oxo132 | 536 |
552 | |
555 | |
567 | |
573 | |
579 | |
582 | |
589 | |
592 | |
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Common terms and phrases
acetate Acta acyl adducts affords alcohols aldehydes aldol reaction alkenes alkylation allylic amines amino acids Analysis of Reagent Angew Asymmetric Synthesis Asymmetry 1991 Buli carbonyl catalyst CHCl3 Chem Chim chiral auxiliary chiral ligand chloride CO2Et CO2H CO2Me Commun./J complex compounds Corey corresponding cyclic cycloaddition cyclopropanation derivatives diastereomeric diastereomers diastereoselectivity Diels–Alder reactions ee eq electrophiles enantiomer enantiomeric excess enantiomerically pure enantioselective Enders Engl enolate epoxidation equiv esters Et2O ether EtOH Evans Form Supplied Helv hydrogenation hydrolysis i-Pr isomer ketones Lewis acid LiAlH4 lithium MeOH methyl Mukaiyama Noyori nucleophiles o-amino obtained optically active Organomet oxidation Perkin Trans Ph Ph Physical Data Precautions Preparative Methods presence prochiral pseudoephedrine racemic reduction Related Reagents Seebach Solubility solvents stereoselective Storage substituted substrates Synlett Synth t-Bu Tetrahedron Lett tion toluene Trost Yamamoto yield