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Is the ras Oncogene Protein a Component of T Kamata and J R Feramisco
In Vitro Correlates of Tumorigenicity of REF52 D B McClure M Dermody and W C
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3T3 cells Acad actin amino acid antigen assay basal cells binding Biochem biological c-src Cancer carcinoma cells catalytic subunit cDNA Cell Biol cell lines cell types cellular Chem clones Cold Spring Harbor containing cultured cytokeratin cytoskeletal desmin detected differentiation epidermal keratin epithelial cells fibroblasts Figure Fuchs Geisler gel electrophoresis gene product genome hybridization immunofluorescence immunoprecipitated intermediate filaments isolated keratin keratinocytes lane large T antigen membrane mesothelial mice microfilaments mitochondria molecules Moll monoclonal antibodies mouse mRNA murine mutant Natl normal nucleotide oncogenes PDBu PDGF peptide phorbol ester phospholipid phosphorylation plasmid platelet-derived growth factor polypeptides Proc protein kinase protein kinase activity purified receptor REF52 cells Rheinwald rhodamine 123 sarcoma virus serum shown specific src gene staining structure SV40-transformed synthesis tein tissue trans transfection transformed cells transforming gene tropomyosin tumor cells tumor promoters two-dimensional gel tyrosine v-src vimentin viral vitro W.W. Franke Weber