Physiological Basis of Aging and Geriatrics, Fourth Edition

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Paola S. Timiras
CRC Press, Aug 16, 2007 - Medical - 536 pages
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Extensively revised and updated to reflect the current state of knowledge in the study of aging, this Fourth Edition offers a complete profile of the aging process at all levels, from molecules and cells to demography and evolution. Written by international experts in current basic and clinical aging research, this text includes aspects of individual, comparative, and differential aging, and discussions of theories and mechanisms of aging. This invaluable reference illustrates how bodily systems, organs, and functions are affected with aging, describes how genetic and environmental factors influence age-related changes, and addresses some of the clinical consequences of these changes for health and longevity. Well illustrated, with numerous tables and graphs, this book presents up-to-date information from internationally renowned experts in various bio-medical fields.

New updated information includes:

  • emphasis on emerging technologies and recent advances in biology and bioengineering that allow greater and longer independence of the elderly
  • recent therapeutic developments in key diseases such as Alzheimer's, osteopenia, osteoporosis, high cholesterol, diabetes, gastritis, sexual impotence, and using transgenic animals as models of aging
  • evaluation of the latest knowledge on the roles of oxidants and antioxidants, and correlates them with other aging-based theories
  • expanded discussion of nutrition and physical exercise
  • chapters on gene and stem cell interventions related to the aging process
  • updated tables to reflect current trends, new research data, and up-to-date statistical information
 

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Contents

Common Terms Related to Aging and Methods Used to Study Aging
3
Chapter 2 Human Longevity in Historical Perspective
11
Chapter 3 Comparative Aging Geriatric Functional Assessment Aging and Disease
23
Chapter 4 Cellular Senscence Cell Death and Transgenic Mouse Models of Aging
41
Chapter 5 Theories of Life Span and Aging
55
Systemic and Organismic Aging
69
Structural Biochemical Metabolic and Circulatory Changes
71
Functional Changes with Aging
89
Atherosclerosis and Coronary Heart Disease
249
Chapter 16 Lipids Lipoproteins and Atherosclerosis
265
Chapter 17 The Pulmonary Respiration Hematopoiesis and Erythrocytes
277
Chapter 18 The Kidney Lower Urinary Tract Body Fluids and the Prostate
297
Chapter 19 The Gastrointestinal Tract and the Liver
315
Chapter 20 The Skeleton Joints and Skeletal and Cardiac Muscles
329
Chapter 21 The Skin
345
Prevention and Rehabilitation
353

Normal Aging Disorders and Treatments of Vision and Hearing in Humans
109
Chapter 9 The Adrenals and PituitaryStress Adaptation and Longevity
137
Chapter 10 Female Reproductive Aging and Menopause
159
Chapter 11 The Ensemble Male HypothalamoPituitaryGonadal Axis
185
Chapter 12 The Thyroid Parathyroid and Pineal Glands
205
Chapter 13 The Endocrine Pancreas Obesity and Diffuse Endocrine and Chemical Mediators
219
Chapter 14 The Immune System
231
Chapter 22 Pharmacology and Drug Management in the Elderly
355
Nutrition and Experimental Strategies in Dietary Restriction
363
Chapter 24 Benefits of Physical Exercise
381
Chapter 25 Regenerative Perspectives and Assistive Technologies
393
Index
399
Back cover
413
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