Biochemistry for the medical sciences
This outstanding text, written in a clear, concise and easy-to-read style, provides students with an in-depth explanation of how each metabolic pathway is directly related to physiology, pharmacology, and clinical medicine. Emphasis is given to those medical problems encountered most frequently in daily clinical practice. Basic metabolism is presented as a coherent part of physiology and reference is made to the matabaolic aberrations seen in clinical situations.
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Thermodynamics in metabolism
Kinetics and metabolism
The oxidation of acetyl coenzymeA
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absorption acetyl-CoA adipose tissue alanine amino acids ammonia anaerobic binding blood glucose concentration brain carbohydrate carbon atoms cells CH2OH changes Chapter cholesterol clinical complex compounds converted cyclic AMP cytosol decrease deficiency degradation diabetes diet disease effect electron transfer electron transfer chain energy enzyme equilibrium excretion fatty acids fibres Figure flux flux-generating step formation fructose fuel gluconeogenesis glucose 6-phosphate glucose utilization glutamate glutamine glycerol glycogen synthase glycolysis hepatic hormone hydrolysis hypoglycaemia important inhibition inhibitor insulin intermediate intestine intracellular involved ions ketone bodies kidney kinase known lactate lipase lipid lipoprotein liver mechanism membrane metabolic pathway mitochondria molecules muscle NAD+ NADH near-equilibrium neurotransmitter normal nucleotides occur oxaloacetate oxidation oxoacids oxygen patients peptide phosphate phosphorylation physiological plasma produced prostaglandins protons pyruvate dehydrogenase ratio reaction catalysed receptor reduced regulation release role Section specific starvation steroid structure substrate cycle Table TCA cycle transport triacylglycerol uptake urea vitamin