Biochemistry for the Medical SciencesThis outstanding text, written in a clear, concise and easy-to-read style, provides students with an in-depth explanation of how each metabolic pathway is directly related to physiology, pharmacology, and clinical medicine. Emphasis is given to those medical problems encountered most frequently in daily clinical practice. Basic metabolism is presented as a coherent part of physiology and reference is made to the matabaolic aberrations seen in clinical situations. |
Contents
Kinetic factors and the metabolic role of | 3 |
Whole animals | 4 |
Thermodynamics in metabolism | 10 |
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2-oxoglutarate acetyl-CoA adipose tissue alanine amino acids ammonia anaerobic blood glucose concentration carbohydrate carbon atoms cell CH₂OH CH₂OPO changes Chapter chemical cholesterol citrate complex compounds converted cytochrome cytosol decrease degradation diabetes disease effect electron transfer chain energy enzyme enzyme activity equilibrium example fatty acids fibres Figure flux flux-generating step formation fructose fuel gluconeogenesis glucose 6-phosphate glutamate glutamine glycerol glycogen glycolysis H₂O hepatic hormone hydrolysis important increase inhibition inhibitor insulin intermediate intestine involved ions ketone bodies kidney kinase known lactate lipase lipid lipoprotein liver mechanism metabolic pathway mitochondria mitochondrial membrane molecules muscle NADH NADPH near-equilibrium non-equilibrium reactions normal nucleotides occur oxaloacetate oxidative phosphorylation oxoacids oxygen patients phosphate physiological plasma produced protein proton pyruvate dehydrogenase ratio reaction catalysed reduced regulation release role Section starvation structure substrate substrate cycle synthase synthesis Table TCA cycle thermodynamic transport triacylglycerol utilization Vmax