Molecular Embryology: How Molecules Give Birth to Animals

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CRC Press, Apr 2, 2002 - Medical - 212 pages
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Molecular Embryology explains in simple terms the molecular interactions that transform an egg to a complex embryo that in the end gives rise to a fully-formed animal. In doing so, the book covers one hundred and fifty years of experiments that have led to our present understanding of these molecular interactions. As the text progresses, the reader will gain a sense of the developmental similarities and differences between organisms. Students studying developmental biology and embryology will find this book an extremely useful introduction to the subject and will also appeal to anyone with an interest in the most recent advances in this largely undiscovered territory.
 

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Contents

Cell Fate and Cell Lineage
7
Cell Division in Frogs
17
CHAPTER Two How AN EMBRYo Acquires
25
Some Cells Migrate to Form Tissues in Distant Parts of
31
Types of Cell Adhesion
37
CHAPTER THREE HOW DIFFERENCES
41
Asymmetric Division and Cell Signaling in Frogs
50
CHAPTER FOUR SIGNAL MOLECULES INDUCE
57
Changing Patterns of Gene Activity along the Length of the Drosophila Embryo
119
Patterns of Gene Activation down Each Side of the Drosophila Embryo
121
The Formation of Cells and Organs of Differing Structure in Drosophila
125
References
129
Further Reading
130
CHAPTER SEVEN THE FRONTIERS OF RESEARCH IN MoLECULAR EMBRYOLOGY 131 Signal Molecules and their Action
131
Recent Research on C Elegans
133
Recent Research on Drosophila
138

Harrisons Experiments on Limb Formation
65
Signaling Cell Position
73
CHAPTER FIVE DIFFERENCES IN EMBRYoNic CEll
79
Weismann Wrongly Suggested that Different Cells of
88
Specific Transcription Factors Are Keys to the Final Step
96
Techniques for Studying the Action of Genes in Development
100
References
108
CHAPTER six ExPERIMENTS ON Drosophila Reveal that SPECIFIC TRANSCRIPTION FACTORS ARE KEYs THAT UNLock EMBRYONic GEN...
111
a Specific Transcription Factor that Initiates Gene Activation from Front to Rear
114
The Bicoid Protein Is a Morphogen
117
Recent Research on Xenopus
141
Recent Research on Mice
144
Recent Research on Limb Development
145
Afterthoughts
146
References
147
Further Reading
148
GLOSSARY
149
INDEX
159
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