Molecular Approaches to Controlling Cancer
Bruce Stillman, David Stewart
CSHL Press, 2005 - Medical - 538 pages
The 2005 Cold Spring Harbor Symposium on Quantitative Biology focused on molecular strategies aimed at understanding and controlling the cancerous state. The resulting volume, with contributions from the world’s leading laboratories, covers many aspects of cancer genetics, including DNA repair, telomeres, animal models, stem cells, and therapeutic approaches.
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Detection of Oncogenic Mutations in the EGFR Gene in LungAdenocarcinoma with Differential Sensitivity to EGFRTyrosine Kinase Inhibitors RK ...
From Specificity toPleiotropic Networks S Grisendi and PP Pandolfi
The Evolving Portrait of Cancer Metastasis PB Gupta S Mani J Yang K Hartwell and RA Weinberg
Genomic Binding and Transcriptional Regulation by theDrosophila Myc and Mnt Transcription Factors A Orian SS Grewal PS Knoepfler BA Edgar ...
Regulation of the Arfp53 Tumor Surveillance Network by E2F PJ Iaquinta A Aslanian and JA Lees
Genetic and Epigenetic Changes in Mammary EpithelialCells Identify a Subpopulation of Cells Involvedin Early Carcinogenesis H Berman J Zhang ...
Epigenetic Changes in Cancer and Preneoplasia JG Herman
A Genetic Approach to Cancer Epigenetics AP Feinberg
TheRole of Extracellular Matrix and Its Degrading Enzymes MJ Bissell PA Kenny and DC Radisky
How Do Cancer Cells Acquire the Fuel Neededto Support Cell Growth? CB Thompson DE Bauer JJ Lum G Hatzivassiliou WX Zong D Ditsworth F ...
Abnormalities of the Inactive X Chromosome Are aCommon Feature of BRCA1 Mutant and SporadicBasallike Breast Cancer S Ganesan AL Richard...
The ATMdependent DNA Damage Signaling Pathway R Kitagawa and MB Kastan
SingleNucleotide Polymorphisms in the p53 Pathway SL Harris G Gil W Hu H Robins E Bond K Hirshfield Z Feng X Yu AK Teresky G Bond and ...
Transcriptional Regulation by p53 and p73 M Lokshin T Tanaka and C Prives
p53Dependent and Independent Functions of theArf Tumor Suppressor CJ Sherr D Bertwistle W den Besten ML Kuo M Sugimoto K Tago RT Willi...
Exploiting the DNA Repair Defect in BRCA Mutant Cells in theDesign of New Therapeutic Strategies for Cancer ANJ Tutt CJ Lord N McCabe H Far...
Identifying Sitespecific Metastasis Genes and Functions GP Gupta AJ Minn Y Kang PM Siegel I Serganova C CordónCardo AB Olshen WL Gerald ...
Roles in Cancer and Oxygen Sensing WG Kaelin Jr
The Src Substrate Tks5 Podosomes Invadopodiaand Cancer Cell Invasion SA Courtneidge EF Azucena Jr I Pass DF Seals and L Tesfay
Modeling Neurofibromatosis Type 1 Tumors in the Mouse forTherapeutic Intervention LF Parada CH Kwon and Y Zhu
Stem Cell SelfRenewal and Cancer Cell ProliferationAre Regulated by Common Networks That Balance theActivation of Protooncogenes and Tumor ...
Prostate Stem Cells and Prostate Cancer DA Lawson L Xin R Lukacs Q Xu D Cheng and ON Witte
Telomererelated Genome Instability in Cancer T de Lange
Telomerase and Cancer Stem Cells M Armanios and CW Greider
Regulation of Telomerase by Human Papillomaviruses DA Galloway LC Gewin H Myers W Luo C Grandori RA Katzenellenbogen and JK McDougall
Genomic Progression in Mouse Models for Liver Tumors AD Tward KD Jones S Yant MA Kay R Wang and JM Bishop
GenotypePhenotype Relationships in a Mouse Model forHuman SmallCell Lung Cancer J Calbó R Meuwissen E van Montfort O van Tellingen and ...
Genetic Analysis of the Role ofCyclindependent Kinases M Barbacid S Ortega R Sotillo J Odajima A Martín D Santamaría P Dubus and M Malumbres
Raising the Bar CFB Kim EL Jackson DG Kirsch J Grimm AT Shaw K Lane J Kissil KP Olive A SweetCordero R Weissleder and T Jacks
Generation and Analysis of Genetically Defined LiverCarcinomas Derived from Bipotential Liver Progenitors L Zender W Xue C CordónCardo GJ ...
Using the Dark Sideof the Force for Cancer Therapy GI Evan M Christophorou EA Lawlor I Ringshausen J Prescott T Dansen A Finch C Martins an...
Chromosomal Translocation Engineering to RecapitulatePrimary Events of Human Cancer A Forster R Pannell L Drynan F Cano N Chan R Codringt...
Deciphering Cancer Complexities in GeneticallyEngineered Mice K Simin R Hill Y Song Q Zhang R Bash RD Cardiff C Yin A Xiao K McCarthy an...
Warburg Addressed DC Wallace
Induction of Complete Regressions of OncogeneinducedBreast Tumors in Mice R Benezra E Henke A Ciarrocchi M Ruzinova D Solit N Rosen D No...
The Fibroblastic Coconspirator in Cancer Progression M Egeblad LE Littlepage and Z Werb
Is Oncogene Addiction Angiogenesisdependent? J Folkman and S Ryeom
Structural Basis for the Functions of EndogenousAngiogenesis Inhibitors MA Grant and R Kalluri
VEGF Trap as a Novel Antiangiogenic Treatment Currently inClinical Trials for Cancer and Eye Diseases and VelociGenebased Discovery of the Nex...
EGFR Mutationsand Response to EGFR Inhibitors DA Haber DW Bell R Sordella EL Kwak N GodinHeymann SV Sharma TJ Lynch and J Settleman
Implications for Control of Cancer SB Baylin and WY Chen
Dissecting Cancer Pathways and Vulnerabilities with RNAi TF Westbrook F Stegmeier and SJ Elledge
Emerging Approaches in Molecular Profiling AffectingOncology Drug Discovery SH Friend
Screens Using RNAi and cDNA Expression as Surrogates forGenetics in Mammalian Tissue Culture Cells J Pearlberg S Degot W Endege J Park J Da...
Cancer Targets in the Ras Pathway P RodriguezViciana O Tetsu K Oda J Okada K Rauen and F McCormick
Subversion of the Bcl2 LifeDeath Switch in CancerDevelopment and Therapy JM Adams DCS Huang A Strasser S Willis L Chen A Wei M Van Delf...
Making Progress through Molecular Attacks on Cancer CL Sawyers
Predicting Clinical Benefit in NonSmallCellLung Cancer Patients Treated with EpidermalGrowth Factor Tyrosine Kinase Inhibitors LC Amler AD Go...
Exploiting the p53 Pathway for the Diagnosisand Therapy of Human Cancer DP Lane
Progress and Challenges inDeveloping Personalized Molecular Cancer Therapeutics P Workman
Modeling of Protein Signaling Networks in Clinical Proteomics DH Geho EF Petricoin LA Liotta and RP Araujo
The Beginning of the End of Frustration Summary T Jacks