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NATURAL AND ACQUIRED IMMUNITY
CELLS AND TISSUES OF THE IMMUNE SYSTEM
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adhesion affinity alleles amino acid anti antigen antigen receptors antigen-specific APCs autoimmune binding bone marrow called CD4+ T cells CD8+ cell activation cell receptor cell surface cell-mediated cell-mediated immunity cellular Chapter class I molecules class II MHC clonal clones complement costimulators CTLs cules cytes cytokines cytoplasmic dendritic cells differentiation disease domains effector encoded endothelial enzymes expression factor foreign antigens function heavy chain helper T cells human IFN-y Ig genes immune responses immune system Immunology induced infections inhibit integrins interactions intracellular isotype leukocytes ligand light chain lymph nodes lymphocytes lymphoid macrophages mast cells mature mechanisms mediated membrane MHC molecules MHC-restricted mice mouse mutations NK cells normal pathway peptides phagocytes phagocytosis plasma produced protein antigens proteins rearrangement recognize region residues role secreted sequences specific immune sponses stimulation strain structure synthesized target cells thymocytes thymus tion tissues transcription transgenic tumor types viral vitro