Parkinson's Disease: Diagnosis & Clinical Management : Second Edition

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Demos Medical Publishing, Dec 15, 2007 - Medical - 1024 pages
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Parkinson's disease (PD) is the second most common neurodegenerative disease in the world. Still the only major text on the subject, the completely revised and updated second edition of Parkinson's Disease: Diagnosis and Clinical Management comes at a time when specialists have made important advances in our understanding of the etiology, pathogenesis, investigation, and management of Parkinson's disease.

The book includes 23 completely new chapters, and has updated information on:

  • Genetics
  • Pathology
  • Biomarkers
  • Pathogenesis
  • Impulse control disorders in Parkinson's disease
  • Updated outcome measures
  • Complementary and alternative medicine for the treatment of Parkinson's disease

Together the chapters form a comprehensive review of the many issues facing PD physicians today. Lucid and easily readable from beginning to end, each chapter may also stand on its own as a scholarly review of the individual subject. Each one is concisely written and heavily referenced for this purpose.

The second edition of Parkinson's Disease: Diagnosis and Clinical Management provides a state-of-the-art review of where we've been, where we are now, and where we are going in treating this disease.

 

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Contents

Past Present and Future
407
35 Rotenone and Other Toxins
437
36 Inflammation
449
37 Genetics
455
A Pharmacologic Miracle Four Decades Later
471
39 Amantadine and Anticholinergics
491
40 Monoamine Oxidase Inhibitors
499
41 Dopamine Agonists
515

10 Gastrointestinal Features
99
11 Autonomic Dysfunction
107
12 Sleep Disorders
119
13 Natural History
127
14 Clinical Rating Scales
135
15 Dementia
147
16 Depression
159
17 Anxiety and Panic
179
18 Apathy and Amotivation
189
19 Impulsecontrol Disorders
201
20 Neuropathology
213
21 Neurochemistry
227
Anatomy and Physiology
245
23 Dopamine Receptor Diversity
267
24 Status of Biological Markers
277
25 Positron Emission Tomography
285
26 Single Photon Emission Computed Tomography
293
27 Magnetic Resonance Imaging
305
28 Controversies in Neuroimaging
317
29 Animal Models
329
Oxidative Stress Mitochondrial Dysfunction and Excitotoxicity
341
31 The Concept and Mechanisms of Programmed Cell Death
357
32 Protein Aggregation
373
The Role of Environment and Genetics
387
42 CatecholOMethyltransferase Inhibitors
533
43 Excitatory Amino Acid Antagonists
545
44 Adenosine A2A Receptor Antagonists
557
45 Complementary and Alternative Medicine
563
46 Motor Fluctuations and Dyskinesia
575
47 Fluctuations of Nonmotor Symptoms
585
48 Psychosis and Other Behaviors
593
49 Treatment of Dementia
613
50 Status of Neuroprotective Therapies
619
51 Symptomatic Treatment Approaches for Early Parkinsons Disease
633
52 Progress in Gene Therapy
643
53 Genetic Testing
655
54 Deep Brain Stimulation
663
Yesterday Today and Tomorrow
689
56 Stereotactic Pallidotomy and Thalamotomy
699
57 Parkinsonsplus Disorders
727
58 Symptomatic Parkinsonism
741
59 Outcome Measures
751
60 Family Caregiving
759
61 Economics
771
62 Driving
779
63 The Patients Perspective
791
Index
799
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About the author (2007)

Stewart A. Factor, DO, Professor and Director Movement Disorder Program, Department of Neurology, Emory University, Atlanta, Georgia

William Weiner, MD, Professor and Chairman, Department of Neurology, University of Maryland, Baltimore, Maryland

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