Ovarian Cancer Immunotherapy

Front Cover
Samir A. Farghaly
Oxford University Press, Sep 28, 2018 - Medical - 272 pages
Ovarian Cancer Immunotherapy provides a broad overview of several aspects of basic sciences, and clinical and therapeutic aspects of immunotherapy for ovarian cancer, as well as state-of-the-art information on molecular genetics and biology. Chapters are written by a team of expert contributors from around the world and explore topics such as antibody therapeutics for ovarian carcinoma, emerging serum biomarkers, ovarian cancer immunity, adoptive cell immunotherapy, the biology of dendritic cells, the role of growth factors, and more. Readers will also gain a better understanding of the molecular and cellular events that underlie ovarian cancer immunology. This book is an ideal resource for clinicians, basic medical scientists, graduate basic medical science students, and medical students caring for patients with ovarian cancer, including attending surgeons and physicians, and clinical fellows and residents in the disciplines of gynecologic oncology, medical oncology, and surgical oncology.
 

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Contents

1 Antibody Therapeutics for Ovarian Carcinoma and Translation to the Clinic
1
2 Biological Aspects and Clinical Applications of Serum Biomarkers in Ovarian Cancer
17
How Does Immune Suppression Grow Cancer?
34
4 Ovarian Tumor Microenvironment and Innate Immune Recognition
48
5 Adoptive Cell Immunotherapy for Epithelial Ovarian Cancer
81
6 AntibodyBased Therapy for Ovarian Cancer
92
7 EpitopePeptideBased Monoclonal Antibodies for Immunotherapy of Ovarian Cancer
115
8 Dendritic Cell Vaccine Therapy for Ovarian Cancer
130
9 Heat Shock Protein Vaccine Therapy for Ovarian Cancer
149
10 PD1PDL1 Inhibitors as Immunotherapy for Ovarian Cancer
170
11 Growth Factors and Their Corresponding Receptors as Targets for Ovarian Cancer Therapy
193
12 Unique Challenges Facing Immunotherapy of Metastatic Ovarian Cancer
205
13 Clinical Trials of Ovarian Cancer Immunotherapy and Future Directions
225
Index
247
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About the author (2018)

Samir A. Farghaly, MD, PhD is a Professor Obstetrics and Gynecology at the Joan and Sanford I. Weill Medical College, Graduate School of Medical Sciences; Sandra and Edward Meyer Cancer Center; and New York-Presbyterian Hospital/Weill Cornell Medical Center in New York, NY. He received his MD and PhD in molecular biology from London University. Dr. Farghaly is the Founder and Editor-in Chief of Current Trends in Gynecologic Oncology, and The International Journal of Gynecological, Obstetrical, and Reproductive Medicine Research. He is a member of the editorial boards of 18 international medical journals on Gynecological Cancers, Gene Expression and Therapy, Women's Health, and Gynecology.

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