The Neurology of AIDS
Neurological complications of progressive HIV-1 infection remain a common cause of morbidity even during widespread use of antiretroviral therapy (ART). Long-term resistance to ART, drug compliance, untoward drug side effects, a myriad of opportunistic infection, depression and other psychiatric disease manifestations, concomitant drug abuse, neuropathies, and an inability to clear viral reservoirs, explain, in large measure, disease progression and immune deterioration. These are associated with a number of psychiatric, muscle, nerve, infectious, as well as cognitive, behavioral, and motor disturbances seen in infected people. Fully updated from the previous two editions and replete with color images, The Neurology of AIDS, Third Edition covers each of these neurological complications and more with a focus on molecular and viral disease processes, cellular factors influencing viral replication therapeutic challenges, and the changing epidemiological patterns of disease. From basic science to clinical care, to epidemiological disease patters, The Neurology of AIDS is the only complete textbook available on AIDS neurology and the only one comprehensive enough to stand alone in each segment of study in brain disorders affected by the human immunodeficiency virus. It is an indispensable resource for students, resident physicians, practicing physicians, and for researchers and experts in the HIV/AIDS field.
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SECTION 1 HIV1 BIOLOGY AND IMMUNOLOGY
SECTION 2 INNATE AND CELLULAR IMMUNITY AND NEUROGENESIS
SECTION 3 BLOODBRAIN BARRIER AND HIV CNS ENTRY
SECTION 4 CELLULAR AND VIRAL NEUROTOXICITY AND ABUSED DRUGS
SECTION 5 ANIMAL MODELS
SECTION 6 PERSONAL PERSPECTIVES IN LIVING WITH HIVAIDS
SECTION 7 CLINICAL AND PATHOLOGIC MANIFESTATIONS OF DISEASE
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