Landmark Papers in Pain: Seminal Papers in Pain with Expert Commentaries
Paul Farquhar-Smith, Pierre Beaulieu, Si n Jaggar
Oxford University Press, Aug 10, 2018 - Medical - 336 pages
Pain Medicine, a relatively new specialty, has proven increasingly relevant to medical practitioners in every field. The specialism of pain has emerged over the past 50 years, largely due to the persistence of experts and new medical evidence that points to its necessity. Today, it is a distinct and integral part of global medical practice. Landmark Papers in Pain offers a comprehensive inventory of over 80 key studies in pain medicine from the last 100 years. Each paper is accompanied by a concise commentary on the significance of the original findings written by an expert in pain. The reviews discuss how the paper influenced the development of the speciality, and how the findings have advanced our global comprehension of pain. Together, the selected papers and reviews chart the growth of an embryonic field into the modern speciality of pain medicine. Complied by leading specialists in the field, the papers included in this book are significant for any student, researcher, clinical practitioner, or medical historian interested in pain medicine. Organised into eight distinct topics and cross-referenced by topics and author of original paper, the book is comprehensive in its coverage and easy to use. A review of the contemporary and historical research that shaped the speciality of pain, Landmark Papers in Pain is essential reading for all medical practitioners with an interest in pain medicine.
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acetaminophen action activity acute afferent agonist anaesthesia anaesthetic analgesic analgesic effects anandamide animal models antinociceptive autotomy behavioural brain breakthrough pain cannabinoid receptor capsaicin cells central sensitization channels chronic pain codeine disease DNIC dorsal horn dose drug efficacy EMLA endocannabinoid endogenous opioids epidural excitatory Experimental fibres fibromyalgia functional gabapentin gene genetic hyperalgesia IASP identified increased inflammatory inhibition inhibitory injection Journal of Pain Journal of Pharmacology landmark paper ligand low back pain mechanisms mediated Medicine Melzack mice modulation Mogil morphine nerve injury neuropathic pain Neuroscience neurotrophins nocebo nociceptive nociceptors opioid receptors pain intensity pain management pain relief pain score pain syndrome paracetamol pathways patient-controlled analgesia patients peptide phantom limb pain post-operative potential pregabalin purinergic reported response role sensory neurons side effects specific spinal cord stimulation subunit surgery symptoms systematic review target therapeutic therapy treatment TRPV1 u-opioid Woolf Yaksh