Landmark Papers in Allergy: Seminal Papers in Allergy with Expert Commentaries
Aziz Sheikh, Thomas Platts-Mills, Stephen Holgate, Allison Worth
OUP Oxford, Feb 28, 2013 - Medical - 319 pages
The increasing incidence and prevalence of allergic disease worldwide is one of the most remarkable phenomena of the past 50 years. One in three people in developed countries will experience an allergic condition at some point in their lives and advances in understanding the causes of this trend, and in allergy treatment and care, have captured the imagination of scientists, clinicians and the public. Landmark Papers in Allergy is a definitive collection of over 90 papers charting key discoveries and scientific advances in relation to allergy and the development of treatment and care for allergic disorders. Comprehensive in its coverage, the book includes the first clear descriptions of allergic diseases; the major advances in treatments, such as the discovery of antihistamines, cortisone, biological therapies and immunotherapy; the great immunological advances, such as the discovery of immunoglobulin E (IgE) and leukotrienes; the possible factors behind the increase in allergy, such as the house dust mite, changes in hygiene and diet; and the growing understanding of the social, psychological and quality-of-life consequences of allergy. Including authoritative commentaries from leading international experts providing reflections on the historical importance and current relevance of each landmark paper, Landmark papers in Allergy is essential reading for any clinician or academic with an interest in allergy.
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Abstract reprinted active airway allergen allergic asthma allergic disease allergic reactions allergic rhinitis allergic sensitization Allergy Clin Immunol anaphylactic anaphylaxis anti-IgE antigen associated Asthma and Allergies atopic dermatitis atopic disease atopic eczema atopy childhood chronic clinical colloid Commentary Copyright cromoglycate cytokines demonstrated desensitization dose double-blind drug dust mite effect endotoxin England Journal environmental eosinophils exposure extract filaggrin food allergy genetic grass pollen hay fever histamine house dust house-dust mite hygiene hypothesis hypersensitivity identified IgE antibodies immune immunoglobulin Immunology immunotherapy impact increased inhaled injection investigators Ishizaka Johansson Journal of Medicine Lancet leukotriene lung mast cells mechanisms Medical observations omalizumab Paper Abstract patients peanut allergy permission from Elsevier placebo placebo-controlled pollen probiotics Professor protein reactivity reaginic receptor reported respiratory response rhinoconjunctivitis risk factors role serum IgE skin tests specific sputum symptoms therapy tion tissue treatment trial urticaria venom Volume wheezing