Opioids in Non-Cancer Pain

Front Cover
OUP Oxford, Mar 21, 2013 - Medical - 112 pages
Opioids have been used as analgesics for many years, and their use in the management of acute pain related to trauma and surgery is well established. However, patients with persisting pain need a pain management plan that brings relief of symptoms without adverse effects in both the short and longer terms. The prescribing of opioids for chronic non-cancer pain has increased substantially since the first edition of this pocketbook was published, prompting considerable debate regarding the appropriateness of prescribing for this indication and the potential harms to individuals and to society that may result from this trend. This second edition of Opioids in Non-Cancer Pain brings clinicians up to date on the current use of opioid drugs in patients with non-cancer pain, and highlights the potential benefits of therapy as well as the problems that can occur. The edition includes new chapters on the history of opioids to help contextualize the following discussions, and a new chapter covering the emerging field of pharmacogenomics which provides explanations for differing responsiveness to opioids and propensity to adverse effects. An international perspective on opioid prescribing trends is also a valuable new addition.

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a brief history
2 Opioid pharmacology
insights from imaging
4 Opioid pharmacogenomics
an international perspective
6 Current good practice in pain medicine
7 Benefits and adverse effects of opioids
pain associated with osteoarthritis
neuropathic pain
13 Practical aspects of prescribing
14 Opioids and addiction
Appendix 1 Prescription writing requirements
Appendix 2 Table of approximate oral analgesic equivalence
Appendix 3 Approximate analgesic equivalences of transdermal opioids
Appendix 4 Calculating the starting dose of methadone inpatient conversion

8 Opioidinduced hyperalgesia
9 Contraindications cautions and drug interactions
back pain

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About the author (2013)

Cathy Stannard is Consultant in Pain Medicine at the Pain Clinic, Macmillan Centre at Frenchay Hospital in Bristol, UK. Michael Coupe is Consultant in Pain Medicine and Anaesthesia at Royal United Hospital, Combe Park, Bath, UK. Tony Pickering is Wellcome Senior Clinical Fellow and Reader inNeuroscience at the School of Physiology and Pharmacology, University of Bristol; Honorary Consultant in Anaesthesia and Pain Medicine, Bristol Royal Infirmary, University Hospitals Bristol, Bristol, UK and Honorary Consultant in Anaesthesia and Pain Medicine, Bristol Royal Infirmary, UniversityHospitals Bristol, Bristol, UK.

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