Landmark Papers in Rheumatology
Richard A. Watts, David G. I. Scott
Oxford University Press, Jun 25, 2015 - Medical - 456 pages
Rheumatic disease is a major cause of morbidity and disability in the Western world. There have been major developments in our understanding of the causes of rheumatic disease and in their treatment during the last half-century, and there are relatively few papers which can be regarded as truly 'landmark' in their construction and subsequent findings.
Part of the Landmark Papers in series, this book provides a detailed review of the seminal papers that have paved the way for breakthroughs in the clinical management of the entire spectrum of rheumatic diseases.
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acid acute alendronate allopurinol ankylosing spondylitis Ann Rheum antibodies antigen arteries Arthritis Rheum assessment associated baseline bisphosphonates bone calcium cardiovascular cells chronic classification criteria clinical trials cohort collagen compared controlled trial coronary CPPD Critique crystals cyclophosphamide demonstrated diagnosis disease activity score dose double-blind drug effects efficacy Ehlers–Danlos syndrome end points measured enthesitis etanercept febuxostat follow-up fracture risk genes genetic gout granulomatosis hydroxychloroquine improvement included increased inflammation inflammatory infliximab involvement joint juvenile idiopathic arthritis knee Lancet Marfan syndrome methotrexate months mutations NEngl observed osteoarthritis osteoporosis outcome pain paper participants pathogenesis patients placebo polyarteritis nodosa population protein psoriatic arthritis radiographic radiological randomized Reference remission renal reported Results Rheum rheumatoid arthritis Rheumatol Rheumatology risk factors rituximab serum shared epitope Significance and importance spondyloarthritis spondyloarthropathies steroids Study design symptoms synovial fluid systemic lupus erythematosus therapy tissue treatment Trial end points urate vasculitis weeks women