For every news story in the popular press detailing the horrors and the violence associated with cocaine, there have been corresponding studies in the medical litera ture shedding new light on our understanding of this most troublesome drug. Our knowledge of addiction, and specifically cocaine addiction, has increased dra matically within the last few years. We stand on the threshold of an exciting new era in addictionology that promises better treatments, improved diagnostic proce dures, and more effective preventative strategies. We must prepare today for the avalanche of exciting dis coveries that will arrive in the coming years. Along with the first two volumes in this series, Marijuana and Alcohol, this book strives to help the general medical community to stay abreast of the latest medical information on addiction, while presenting a fundamental resource on the neurobiology, physiology, epidemiology, history, diagnosis, treatment, and p- v vi PREFACE vention of cocaine abuse. In addition, the comorbidity of cocaine abuse and eating disorders, depression, anx iety, hypertension, and various other disorders is dis cussed in detail. Finally, the last chapter presents new strategies tailored to specific patient groups and aimed at confronting the ever-changing face of drug abuse.
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Cocaine in the 1990s
The History of Cocaine
The Neurobiology of Cocaine
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abstinence abused drugs acute adolescents adults alcohol amantadine amphetamines anorexia nervosa antagonist antidepressant associated with cocaine brain reward bromocriptine bulimia buprenorphine caine carbamazepine chronic cocaine cigarettes clinical clinicians cocaine abuse cocaine addiction cocaine administration cocaine dependence cocaine users cocaine-induced cocaine's crack craving decreased depression desipramine dopamine dopamine transporter dose drawal drug abuse drug screens drug testing drug users drug-free Drugs and Alcohol drugs of abuse eating disorders effects of cocaine employee ETOH euphoria factors freebase Gold high school seniors hospital illegal drugs illicit drugs increased inhibit inpatient Institute on Drug intravenous legalization locus coeruleus marijuana MDMA ment naltrexone neurons neurotensin nucleus accumbens opiate opioid outpatient patients Pergolide Pharmacol pharmacological physicians problems psychiatric psychological rats recent receptors reinforcement relapse reported response result risk self-administration smoking stimulation strategies study found substance abuse suggest symptoms tested positive therapy tion treat treatment programs urine York