Clearing the Smoke: Assessing the Science Base for Tobacco Harm Reduction
Institute of Medicine, Board on Health Promotion and Disease Prevention, Committee to Assess the Science Base for Tobacco Harm Reduction
National Academies Press, Oct 17, 2001 - Medical - 656 pages
Despite overwhelming evidence of tobacco's harmful effects and pressure from anti-smoking advocates, current surveys show that about one-quarter of all adults in the United States are smokers. This audience is the target for a wave of tobacco products and pharmaceuticals that claim to preserve tobacco pleasure while reducing its toxic effects.
This book looks at the types of products that could reduce harm and reviews the available evidence for their impact on various forms of cancer and other major ailments. It also recommends approaches to governing these products and tracking their public health effects.
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EXECUTIVE SUMMARY 1
INTRODUCTION BACKGROUND AND CONCLUSIONS
Health Impact of LowYield Products 66
Potential Influence of PREPs on Tobacco Use Behaviors 73
TOBACCOSMOKE AND TOXICOLOGY 283
EXPOSURE AND BIOMARKER ASSESSMENT IN HUMANS 309
CARDIOVASCULAR DISEASE 470
NONNEOPLASTIC RESPIRATORY DISEASES 500
REPRODUCTIVE AND DEVELOPMENTAL EFFECTS 543
OTHER HEALTH EFFECTS 560