Holland Frei Cancer Medicine Eight, Volume 8

Front Cover
PMPH-USA, 2010 - Medical - 2021 pages
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The consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists and others who treat cancer patients, Cancer Medicine 8 covers the ever-widening sphere of current cancer knowledge and clinical practice.

In this new 8th edition an outstanding editorial team from world-renowned medical centers continues to hone the leading edge forged in previous editions, with timely information on biology, immunology, etiology, epidemiology, prevention, screening, pathology, imaging and therapy.

The book is a testament to the editorial panel's creed that innovative, comprehensive, multidisciplinary treatment of cancer patients must be grounded in a fundamental understanding of cancer biology. Cancer Medicine 8 does a superb job of bringing scientific principles into clinical practice. This text is the ultimate resource of new information providing the basis for better informed cancer therapy choices.

Cancer Medicine 8 features hundreds of 4-color illustrations, photographs, tables, graphs and algorithms that make this text an invaluable clinical tool in recognizing characteristic appearances of both patient and tissue.

The 137 tightly focused chapters are organized into 5 sections:

I: Cardinal Manifestations of Cancer
II: Scientific Foundations of Cancer
III: Principles of Cancer Diagnosis
IV: Principles of Therapeutic Modalities
V: Principles of Multidisciplinary Management

Major Revisions:

Chapter 6: Oncogenes An entire section is devoted to oncogenes like kit, Ret, Braf, Akt genes and the new drugs that specifically target them. This chapter not only provides a list of these new therapies but also insight as to how they target the oncogenes and their mutations, as well as therapy response and efficacy.
Chapter 11: Tumor Angiogenesis This chapter provides a wealth of new data and understanding of the mechanisms of angiogenesis and how it contributes to the malignancy of various cancers The Clinical Advancement section provides an extensive summary of new trials investigating numerous novel angiogenesis agents
Chapter 33: Chemoprevention This chapter also provides a considerable amount of new information for a broad range of clinical trials such as the HPV vaccine trial Future, Select, Star, Approve and PreSAP. The rationales for these trials are discussed and resulting data from the completed trials are presented.
Chapter 55: Cytokines Research on cytokines is another area that is exploding in magnitude. This chapter presents a wealth of new information on promising new therapeutic agents.There is also updated information on the therapeutic usage of currently available agents such as hemotopoietic growth factors (HGF), erythropoietin and thromobopoietic agents.
Chapter 56: Monoclonal Serotherapy A considerable amount of research has been done in the past few years on therapeutic and targeted agents in cancer therapy. Updated information and data is provided from recent trials for therapies previously discussed in Cancer Medicine edition 7 covering therapeutic agents and targeted toxins.
Chapter 77: Neoplasms of the Head and Neck There is a discussion of changes in treatment methods for certain cancers such as the recent shift from surgery to combined chemotherapy with radiotherapy for tonsillar cancer, nasal and paranasal sinuses cancers and laryngeal cancer.
Chapter 78: Lung Cancer Advances in diagnostic techniques are described such as ultrasound-guided fine needle aspiration or electromagnetic navigation diagnostic bronchoscopy. Video assisted thoracoscopic surgery (VATS) discussion is updated. New sections are devoted to prognostic and predictive biomarkers.

 

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Contents

I
1
II
5
V
26
VI
40
VII
51
VIII
68
IX
86
X
102
XCIII
899
XCIV
904
XCVI
915
XCVII
923
XCIX
933
C
940
CI
959
CIII
999

XI
125
XIII
141
XIV
149
XV
170
XVI
175
XVII
190
XVIII
225
XIX
237
XX
248
XXI
262
XXII
270
XXIII
279
XXIV
291
XXV
298
XXVI
302
XXVII
311
XXVIII
318
XXIX
335
XXXI
347
XXXIII
359
XXXIV
364
XXXV
371
XXXVI
386
XXXVII
398
XXXVIII
411
XXXIX
419
XL
446
XLII
464
XLIV
473
XLV
489
XLVII
490
XLVIII
499
XLIX
510
LI
528
LIII
541
LV
550
LVI
558
LVII
568
LVIII
587
LIX
597
LX
611
LXII
621
LXIV
633
LXV
645
LXVII
655
LXIX
679
LXXI
686
LXXII
710
LXXIII
725
LXXIV
737
LXXVI
750
LXXVII
759
LXXVIII
776
LXXIX
793
LXXXI
810
LXXXII
823
LXXXIV
830
LXXXV
838
LXXXVI
846
LXXXVIII
854
LXXXIX
863
XCI
881
CV
1044
CVII
1053
CVIII
1062
CIX
1067
CX
1074
CXI
1086
CXII
1109
CXIV
1124
CXV
1132
CXVII
1144
CXIX
1172
CXX
1194
CXXII
1204
CXXIII
1212
CXXIV
1219
CXXVI
1228
CXXVII
1255
CXXVIII
1263
CXXIX
1289
CXXX
1299
CXXXII
1325
CXXXIV
1338
CXXXV
1344
CXXXVI
1376
CXXXVII
1384
CXXXVIII
1393
CXL
1459
CXLI
1487
CXLII
1497
CXLIV
1517
CXLV
1544
CXLVI
1559
CXLVII
1582
CXLIX
1591
CL
1604
CLI
1622
CLIII
1645
CLIV
1659
CLVI
1668
CLVIII
1686
CLIX
1696
CLXI
1713
CLXII
1723
CLXIV
1740
CLXVI
1757
CLXVIII
1763
CLXIX
1779
CLXX
1788
CLXXI
1797
CLXXII
1813
CLXXIII
1823
CLXXV
1832
CLXXVI
1849
CLXXVII
1871
CLXXVIII
1880
CLXXX
1891
CLXXXI
1901
CLXXXIII
1915
CLXXXIV
1921
CLXXXV
1941
CLXXXVII
1961
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About the author (2010)

Waun Ki Hong, MD Division Head Thoracic Head & Neck Medical Oncology, MD Anderson Cancer Center

Donald W. Kufe, MDProfessor of MedicineDana Farber Cancer InstituteHarvard Medical School

Robert C. Bast Jr, MDVice President for Translation ResearchMD Anderson Cancer Center

William Hait, MD, PhDSenior VP and Worldwide Head Ortho Biotech Oncology Research & Development (ORD), Johnson & Johnson Pharmceutical Research & Development

Raphael E. Pollock, MD, PhDHead of the Division of Surgery, Professor and Chairman of the Department of Surgical Oncology, Senator A. M. Aiken, Jr. Distinguished Chair M. D. Anderson Cancer Center

Ralph R. Weichselbaum, MDDaniel K. Ludwig ProfessorChair Dept of Radiology and Cellular OncologyUniversity of Chicago HospitalDirector Chicago Tumor Institute

James F. Holland, MD, ScD (hc)Director Emeritus, Derald H. Ruttenberg Cancer CenterMount Sinai School of Medicine

Emil Frei, III, MDPhysician in Chief EmeritusDana Farber Cancer Institute

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