Chemiluminescence and Bioluminescence: Past, Present and FutureAldo Roda This complete and well-organized overview of chemiluminescence and bioluminescence is divided into two parts. The first covers historical developments and the fundamental principles of these phenomena before going on to review recent advances and instrumentation. The second deals with applications in a variety of research fields including life sciences, drug discovery, diagnostics, environment, agrofood, and forensics. The book also includes a comprehensive collection of recent bibliographic references. It is suitable not only for researchers currently employing detection techniques in their research activity, but also for those approaching the subject for the first time. This book is a comprehensive overview of bioluminescence and chemiluminescence, from the basic principles and the most common luminescent systems to their applications in different fields - from analytical chemistry to biotechnology, miniaturized analytical devices, life sciences (whole-cell biosensors, bioluminescence molecular imaging) and multiplexed assays. Written by an expert, who for many years has been involved in the development of bio- and chemiluminescent (bio)analytical methods, this book documents the latest research in luminescence, thus representing the most updated reference text for people interested in the field. |
Contents
Miniaturized Analytical Devices Based | 543 |
References | 554 |
A History of Bioluminescence and Chemiluminescence from | 3 |
9 | 43 |
The Nature of Chemiluminescent Reactions | 51 |
References 571 | 85 |
Past Present and Future | 91 |
Instrumentation for Chemiluminescence | 113 |
of ATP | 166 |
Flowassisted Analysis | 191 |
Analytical Applications of Chemiluminescence | 227 |
Acknowledgements | 278 |
Chemiluminescence to Immunoassays | 289 |
References | 325 |
Gene Assays Based on BioChemiluminescence | 334 |
References | 375 |
4 | 114 |
7 | 120 |
23 | 135 |
Classical Applications of Chemiluminescence | 143 |
27 | 151 |
51 | 158 |
Ultrasensitive Bioanalytical Imaging | 398 |
References | 421 |
Biotechnological Improvements of Bioluminescent | 443 |
Acknowledgements | 476 |
Chemiluminescent and Bioluminescent Biosensors | 488 |
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acid acridinium ester Acta aequorin Anal analysis analytical antibody antioxidant antioxidant activity applications automated bacterial Bioanal Biochem Biol bioluminescence bioluminescence imaging biosensors biotinylated buffer camera capillary cells Chem chemical chemiluminescence Chemistry Chim chip Chromatogr CL detection CL emission CL reaction CL reagent CL signal CLIA Clin compounds concentration conjugate detection limit detector determination developed dinoflagellates dioxetane electron EMCCD emit light enhancer enzyme ester extracts Figure firefly luciferase flow fluorescent gene hybridization assay hydrogen peroxide imaging immobilized immunoassay injection J. W. Hastings kinetics label light emission luciferin luminescence luminol luminometer luminous measurement method microarray microchip microfluidic microtiter molecular molecules monitoring mutant Natl oxidation oxygen performed photomultiplier photon photoprotein pixel probe production protein quantitative radical range reagent Renilla luciferase reported Roda sample sensitivity Shimomura specific streptavidin substrate target DNA techniques vivo Wang Zhang