The Blood Group Antigen FactsBookThe second edition of The Blood Group Antigen FactsBook provides key information relating to human red blood cell membrane components carrying blood group antigens, the molecular basis of the antigens, their serological characteristics, and the clinical significance of blood group antibodies. The data on this group of molecules has expanded greatly since the previous edition was published five years ago. Topics include: history and information on terminology, expression, chromosomal assignment, carrier molecule description, molecular basis of antigens, effect of enzymes/chemicals, clinical significance, disease association, phenotypes, glycotypes and key references.
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Common terms and phrases
200 mM Resistant antibody antigen on intact ANTIGEN Terminology ISBT antigen1 Amino acid Antithetical antigen binding No Clinical Blacks blood group system cells class IgG Optimal Clinical significance Comments common containing COOH Cord RBCs Expressed domain Effect of enzymes/chemicals encoded et al example exon Expressed Molecular basis Expression Cord RBCs Ficin/papain Resistant Trypsin Gene glycophorin History IAT Complement binding identified IgG Optimal technique Immunoglobulin class IgG intact RBCs Ficin/papain ISBT symbol number known membrane Mild Molecular basis associated mutation names Nucleotide Occurrence All populations Optimal technique IAT phenotype Presumed resistant proband Product Pronase Sensitive Sialidase protein Rare RBCs Ficin/papain Resistant References residues Resistant Acid Resistant Resistant DTT 200 Resistant DTT 200mM/50mM Resistant In vitro Resistant Pronase resistant Sialidase result sera serum severe Sialidase Resistant DTT specificity technique IAT Complement Terminology ISBT symbol Transfusion reaction vitro characteristics Vox Sang Weak
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Page x - The New York Blood Center, 310 East 67th Street. New York, NY 10021. Tel. 212/570-3075; Fax 212/570-3195. detailed "Guide to Authors" is obtainable from the Tice of the Managing Editor.
Page 9 - Val alanine arginine asparagine aspartic acid cysteine glutamine glutamic acid glycine histidine isoleucine leucine lysine methionine phenylalanine proline serine threonine tryptophan tyrosine valine in which case four amino acids would be coded for.
Page 15 - K., 1976. The Distribution of the Human Blood Groups and Other Polymorphisms, 2nd edition. Oxford University Press, London.
Page 15 - Race, RR, and Sanger, R., 1975. Blood Groups in Man, 6th edition. Blackwell Scientific Publications, Oxford, London, Edinburgh, Melbourne, pp.
Page 19 - In 1900, Landsteiner mixed sera and RBCs from his colleagues and observed agglutination. On the basis of the agglutination pattern, he named the first two blood group antigens A and B, using the first letters of the alphabet. RBCs not agglutinated by either sera were first called C but became known as "ohne A" and "ohne B" (ohne is German for "without") and finally O.