PlateletsAlan D. Michelson Platelets - winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine - is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource.
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a-granules Acad Sci USA acid actin activated platelets agonists allbẞ3 angiogenesis antibodies arterial associated binding Biochem Biol Chem bleeding Ca2+ Cell Biol Chapter circulating Clin Invest coagulation collagen complex coronary cytoplasmic cytoskeleton dense granules disease endothelial cells expression extracellular factor XI fibrin fibrinogen gene genetic GPIb-IX-V GPIba GPVI Haematol hemostasis human platelets identified induced inhibition inhibitor integrin interaction kinase leukocytes ligand mechanism mediated megakaryocytes mice microparticles microRNA microtubule molecular molecules mouse mutations Natl Acad Sci nitric oxide nitric oxide synthase P-selectin pathway patients PECAM-1 phosphorylation plasminogen plate platelet activation platelet adhesion platelet aggregation platelet function platelet glycoprotein platelet membrane platelet surface platelet-derived polymorphism Proc Natl Acad proplatelet prostacyclin protein proteome prothrombinase receptor regulation release response role sequence signaling structure studies subunit syndrome telets Thromb Haemost thrombin thrombocytes thrombosis thrombus formation tion tissue TXA2 tyrosine vascular vitro vivo von Willebrand factor Willebrand factor