Materials and Devices for Bone DisordersSusmita Bose, Amit Bandyopadhyay Materials for Bone Disorders is written by a cross-disciplinary team of research scientists, engineers, and clinicians and bridges the gap between materials science and bone disorders, providing integrated coverage of biomaterials and their applications. The bioceramics, biopolymers, composites, and metallic materials used in the treatment of bone disorders are introduced, as are their interactions with cells, biomolecules, and body tissues. The main types of bone disorder and disease are covered including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders. Bone disorders are common across all ages. Various forms of bone disorders can change the lifestyle of otherwise normal and healthy people. With the development of novel materials, many forms of bone disorders are becoming manageable, allowing people to lead a fairly normal life. Specific consideration is given to areas where recent advances are enabling new treatments, such as the use of resorbable ceramics in bone tissue engineering and drug delivery, newer polymer-based implants in load-bearing contexts, and engineering biomaterials surfaces including modifying surface chemistry. Ethical and regulatory issues are also explored. - Explores biomaterials for bone repair and related applications in orthopedics and dentistry in a clinical context - Introduces biomaterials applications in the context of specific diseases, bone disorders, and theraputic contexts - Includes input from a world-class team of research scientists, engineers, and clinicians - Covers the main types of bone disorder and disease including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders |
Contents
3 Bone Disorders | 83 |
4 Implants for Joint Replacement of the Hip and Knee | 119 |
5 Material and Mechanobiological Considerations for Bone Regeneration | 197 |
6 Ceramics in Bone Grafts and Coated Implants | 265 |
7 Ceramic Coatings in LoadBearing Articulating Joint Implants | 315 |
8 Polymers and Composites for Orthopedic Applications | 349 |
9 Surface Modifications and Surface Characterization of Biomaterials Used in Bone Healing | 405 |
10 Predictive Methodologies for Design of Bone Tissue Engineering Scaffolds | 453 |
11 Ethical Issues in Biomaterials Research | 493 |
12 Research on Bone DisordersFrom Ideas to Clinical Use ProductThe Path to Commercialization | 505 |
13 Current Challenges and Future Needs in Biomaterials and Devices for Bone Disorders | 517 |
| 527 | |
Back Cover | 544 |
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Common terms and phrases
3D printed acetabular acid Acta Biomater alloy applications Available Bandyopadhyay bioceramics biocompatibility biodegradable bioglass biological biomaterials Biomed Mater Res biomedical bisphosphonates bone cement bone defects bone disorders bone formation bone graft bone graft substitute Bone Joint Surg bone regeneration bone resorption bone tissue engineering boride Bose calcium phosphate cementless ceramic chondrosarcoma Clin Orthop Relat clinical coating collagen components compressive degradation density devices differentiation disease drug effect enhanced femoral head fixation fracture function growth factor healing hip replacement hydrogels hydroxyapatite improve increased interactions interface load load-bearing long-term materials matrix mechanical properties mesenchymal stem cells modulus molecular Orthop Relat Res orthopedic osteoblasts osteoconductive osteocytes osteogenic osteolysis osteoporosis particles patients plasma PMMA polyethylene polymer porosity porous protein resorbable sintering stem cells strength substrate surface surgery techniques tion tissue engineering titanium total hip arthroplasty total knee treatment tumor UHMWPE vitro vivo wear