Essentials of Micro- and Nanofluidics: With Applications to the Biological and Chemical SciencesThis book introduces students to the basic physical principles to analyze fluid flow in micro and nano-size devices. This is the first book that unifies the thermal sciences with electrostatics and electrokinetics and colloid science; electrochemistry; and molecular biology. The author discusses key concepts and principles, such as the essentials of viscous flows, an introduction to electrochemistry, heat and mass transfer phenomena, elements of molecular and cell biology, and much more. This textbook presents state-of-the-art analytical and computational approaches to problems in all of these areas, especially electrokinetic flows, and gives examples of the use of these disciplines to design devices used for rapid molecular analysis, biochemical sensing, drug delivery, DNA analysis, the design of an artificial kidney, and other transport phenomena. This textbook includes exercise problems, modern examples of the applications of these sciences, and a solutions manual available to qualified instructors. |
Contents
Preparatory Concepts | 40 |
The Governing Equations for an Electrically Conducting Fluid | 74 |
The Essentials of Viscous Flow | 140 |
Heat and Mass Transfer Phenomena in Channels and Tubes | 180 |
Introduction to Electrostatics | 213 |
Elements of Electrochemistry and the Electrical Double Layer | 230 |
Elements of Molecular and Cell Biology | 283 |
Electrokinetic Phenomena | 306 |
Essential Numerical Methods | 348 |
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analytical approximation assumed biomolecules boundary conditions boundary layer C/m² calculated cell chapter charge density chemical concentration constant Debye length defined depicted in Figure derivative devices differential equations diffusion coefficient dimensional dimensionless dimensionless form discussed electric field electrical potential electro-osmotic flow electrokinetic electrolyte electrons electrostatics energy example flow rate fluid mechanics flux force formula fully developed function given governing equations gradient heat and mass heat transfer integral ion channels ionic linear liquid mass transfer Matlab methods micro microfluidic mixture mole fraction molecular molecules nanofluidics nanopore nanopore membrane nanoscale negatively charged no-slip condition Note numerical solution parameters particle Poiseuille flow polynomial pressure problem proteins radius result Reynolds number simulations solved species streamwise surface charge density Taylor series temperature thermal thermodynamics transport tube velocity viscosity volume wall zero ди ду дх