Molecular Cell Biology

Harvey F. Lodish

Macmillan, 2008 - Science - 973 pages

With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, Molecular Cell Biology has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors.

Contents

• CONTENTS IN BRIEF: 1-1
• Human Medicine Is Informed by Research on Other: 1-29
• Stereoisomers in medication p: 1-33
• The Hydrophobic Effect Causes Nonpolar: 1-63
• Part II: 1-64
• Part III: 1-71
• Diseases of protein misfolding p: 1-77
• Drugs can inhibit protein activity p: 1-84
• BASIC MOLECULAR GENETIC: 1-111
• MethionyltRNAMET Recognizes the AUG Start Codon: 1-133
• Colon cancer p 148: 1-148
• Viruses such as HIV and HPV attack our cells p 159: 1-159
• Translation Is Terminated by Release Factors: 1-166
• Hemoglobin alleles affect sicklecell anemia and malaria: 1-167
• HighFidelity DNA ExcisionRepair Systems: 1-178
• DNA microarrays are powerful diagnostic tools in medicine: 1-193
• Many Inherited Diseases Result from Multiple Genetic: 1-203
• Knockout mice are used to study cystic fibrosis p 208: 1-208
• Microsatellites cause neuromuscular diseases p 224: 1-224
• Mobility of L1 elements causes many genetic diseases p 232: 1-232
• Antibiotics have different effects on mitochondrial: 1-240
• Comparison of Related Sequences from Different: 1-244
• Using human telomerase inhibitors to treat cancer p 264: 1-264
• Chromatin Exists in Extended and Condensed Forms: 1-265
• transcriptional Control: 1-269
• Regulatory Elements in Eukaryotic DNA Are Found: 1-276
• Polymerase II: 1-278
• Absence of repressor activity in genes causes cancer p 290: 1-290
• Transcription Preinitiation Complex in Vitro: 1-297
• Xeroderma pigmentosum and Cockaynes syndrome p 298: 1-298
• Repressors Can Direct Histone Deacetylation: 1-303
• The Yeast TwoHybrid System Exploits Activator Flexibility: 1-310
• Exon skipping and spinal muscle atrophy p 333: 1-333
• Microsatellites regions and neurological diseases p 340: 1-340
• Thalassemia p 346: 1-346
• mTOR pathway and human cancers p 355: 1-355
• Cell Structure and Function: 1-371
• TaySachs disease p 374: 1-374
• Plant Vacuoles Store Small Molecules and Enable: 1-377
• Biomembrane Structure: 1-409
• HAT Medium Is Commonly Used to Isolate: 1-431
• Atherosclerosis and cholesterol p 432: 1-432
• Transmembrane Transport of lons and Small Molecules: 1-437
• Aquaporin vasopressin and diabetes insipidus p 445: 1-445
• ABC proteins and cystic fibrosis p 455: 1-455
• Na+K+ ATPase and heart muscle contractions p 468: 1-468
• Cellular Energetics: 1-479
• Cyanide inhibits cellular respiration p 498: 1-498
• Rotation of the F₁ y Subunit Driven: 1-506
• ATPADP antiporter activity and herbal remedies p 509: 1-509
• 13: 1-533
• Cytosolic Receptor Targets Proteins with an: 1-542
• Emphysema and protein misfolding p 555: 1-555
• Defective peroxisome assembly can lead to craniofacial: 1-568
• 14: 1-579
• Cystic fibrosis p 593: 1-593
• Lysosomal storage diseases p 602: 1-602
• Familial hypercholesterolemia FH and LDL cholesterol: 1-608
• Signal Transduction and ShortTerm Cellular Responses: 1-623
• Asthma treatment p 629: 1-629
• Bacterial toxins and G proteins p 639: 1-639
• That Regulate lon Channels: 1-640
• Nitroglycerin and angina p 556: 1-660
• Signaling Pathways That Control Gene Activity: 1-665
• Conserved Domains Are Important for Binding Signal: 1-682
• Vesicles Coated with Clathrin andor Adapter Proteins: 598
• Several Pathways Sort Membrane Proteins to: 631
• Negative Feedback Loops Regulate TGFẞSmad: 648
• Protein Cleavage: 665
• Overexpression of HER2 a Receptor: 680
• Binding of Sos Protein to Inactive Ras Causes: 707
• 17: 713
• GPCRBound Arrestin Activates Several Kinase Cascades 698: 724
• Toxins That Perturb the Pool of Actin Monomers: 726
• 637: 754
• Microtubules and Intermediate Filaments: 757
• Individual Microtubules Exhibit Dynamic Instability: 763
• MyosinVBound Vesicles Are Carried Along: 769
• Centrosomes Duplicate Early in the Cell Cycle: 783
• 19: 801
• Defects in Lamins and Keratins Cause Many Diseases: 824
• Cell Growth and Development: 847
• Nuclear Envelope Depend on Dephosphorylation: 870
• 120: 896
• Tension on Spindle Microtubules Contributes: 930
• Proteins That Regulate Asymmetry Are Localized: 931
• A Cascade of Caspase Proteins Functions in: 938
• The Molecular Cell Biology of Development: 949
• According to Maternal or Paternal Chromosome: 991
• Nerve Cells: 1001
• CLASSIC EXPERIMENT 14 1 Following a Protein: 1004
• The Nervous System Uses Signaling Circuits: 1027
• 960: 1035
• All VoltageGated lon Channels Have Similar: 1037
• Action Potentials Jump from Node to Node: 1043
• Neurotransmitters Are Transported into Synaptic: 1055
• Inflammation Is a Complex Response to Injury That: 1061
• The Killing Activity of Cytotoxic T Cells Is Antigen: 1107
• Specific Mutations Transform Cultured Cells: 1113
• CancerCausing Viruses Contain Oncogenes: 1121
• Promoting Proteins: 1127

Bibliographic information

• Title: Molecular Cell Biology
• Author: Harvey F. Lodish
• Edition: illustrated
• Publisher: Macmillan, 2008
• ISBN: 0716776014, 9780716776017
• Length: 973 pages
• Subjects: Science / Life Sciences / Biology; Science / Life Sciences / Cell Biology; Science / Life Sciences / Molecular Biology