Autoimmune Liver Disease: Management and Clinical Practice

Front Cover
James Neuberger, Gideon M. Hirschfield
John Wiley & Sons, Apr 13, 2020 - Medical - 336 pages

A practical guide to autoimmune liver diseases through pathogenesis, diagnosis, and management

In Autoimmune Liver Disease Management and Clinical Practice, practitioners will learn about the current state of autoimmune liver disease and how to focus on their diagnosis and treatment. The four-part book begins with a thorough investigation of current immunological thinking as it relates to the autoimmunity of the liver. It also covers the four major hepatic autoimmune liver diseases in both adults and children, their management and the role of liver transplantation, and learned approaches to patient management and empowerment.

Expert authors in the field have come together to provide a thorough examination of autoimmune liver disease to help support clinicians assisting patients. The text provides an in-depth look at topics including:

● The four major hepatic autoimmune liver diseases, their diagnosis, and potential disease management

● The use (and misuse) of autoantibodies in diagnosis and treatment

● The role and timing of liver transplantation and the impact of recurrent autoimmune liver disease as well as de novo autoimmune hepatitis

● Optimal approaches to managing patients and keeping care personalised

With breadth, depth and current-day relevance, Autoimmune Liver Disease sheds light on recent developments in management of liver disease for practitioners, nurses, and health care professionals.

 

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Contents

Scientific Basis of Clinical Autoimmune Liver Diseases
5
Drug Metabolism 11
11
Biochemical Markers and Patterns of Hepatic Injury 17
17
Concepts of Autoimmunity Relevant to Autoimmune Liver Diseases 21
21
References
44
3
47
Autoantibodies and Understanding of Autoimmune Liver Diseases
65
Environmental Exposure and Risk in Autoimmune Liver Diseases
83
Specific Clinical Challenges
181
Managing Pregnant Women with Autoimmune Liver Disease
201
Bone Health in Patients with Autoimmune Liver Diseases
219
Transplantation and Its Role in Autoimmune Liver Disease
233
Recurrent Autoimmune Liver Disease and its Scientific Significance
247
Controversies in Autoimmune Liver Diseases
263
The Role of Extrahepatic Autoimmunity in Autoimmune Liver Disease
277
Symptoms Chronic Disease and Patient Management
289

Autoimmune Liver Diseases and Their Clinical Correlation
103
References
118
8
143
9
163
Key Concepts
291
Effective Care Delivery in AILD
299
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About the author (2020)

JAMES NEUBERGER studied at Oxford and trained at the Liver Unit, Kings College Hospital, in London. He has researched and written about liver disease and liver transplantation for over 35 years, including editing five books and serving as the editor of Transplantation and associate editor of The Journal of Hepatology. He is currently a consultant physician in the Liver Unit, Queen Elizabeth Hospital, Birmingham, UK.

GIDEON M. HIRSCHFIELD is a clinician-scientist and expert in autoimmune liver disease practice and science. His experience spans many years in transplant Hepatology in North America and the United Kingdom, including numerous published works. He currently has a practice at the University of Toronto, Ontario, Canada.

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