Statistical Models in Epidemiology, the Environment, and Clinical Trials

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M.Elizabeth Halloran, Donald Berry
Springer Science & Business Media, Dec 6, 2012 - Medical - 283 pages
This IMA Volume in Mathematics and its Applications STATISTICAL MODELS IN EPIDEMIOLOGY, THE ENVIRONMENT,AND CLINICAL TRIALS is a combined proceedings on "Design and Analysis of Clinical Trials" and "Statistics and Epidemiology: Environment and Health. " This volume is the third series based on the proceedings of a very successful 1997 IMA Summer Program on "Statistics in the Health Sciences. " I would like to thank the organizers: M. Elizabeth Halloran of Emory University (Biostatistics) and Donald A. Berry of Duke University (Insti tute of Statistics and Decision Sciences and Cancer Center Biostatistics) for their excellent work as organizers of the meeting and for editing the proceedings. I am grateful to Seymour Geisser of University of Minnesota (Statistics), Patricia Grambsch, University of Minnesota (Biostatistics); Joel Greenhouse, Carnegie Mellon University (Statistics); Nicholas Lange, Harvard Medical School (Brain Imaging Center, McLean Hospital); Barry Margolin, University of North Carolina-Chapel Hill (Biostatistics); Sandy Weisberg, University of Minnesota (Statistics); Scott Zeger, Johns Hop kins University (Biostatistics); and Marvin Zelen, Harvard School of Public Health (Biostatistics) for organizing the six weeks summer program. I also take this opportunity to thank the National Science Foundation (NSF) and the Army Research Office (ARO), whose financial support made the workshop possible. Willard Miller, Jr.
 

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Contents

UNMEASURED CONFOUNDING IN MISSING DATA
2
Sections 611 by J M Robins
31
21205
91
Marginal structural models versus structural nested
93
Nonparametric locally efficient estimation of
135
A
179
Markov chain Monte Carlo methods for clustering
193
A simulation study of the epidemiological impact
219
The use of reference priors and Bayes factors
237
Surrogate endpoints in cancer clinical trials
251
List of Participants
273
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