Physical Sciences and Engineering Advances in Life Sciences and Oncology: A WTEC Global Assessment

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Paul Janmey, Daniel Fletcher, Sharon Gerecht, Ross Levine, Parag Mallick, Owen McCarty, Lance Munn, Cynthia Reinhart-King
Springer, Nov 19, 2015 - Science - 403 pages

This book presents an Assessment of Physical Sciences and Engineering Advances in Life Sciences and Oncology (APHELION) by a panel of experts. It covers the status and trends of applying physical sciences and engineering principles to oncology research in leading laboratories and organizations in Europe and Asia.

The book elaborates on the six topics identified by the panel that have the greatest potential to advance understanding and treatment of cancer, each covered by a chapter in the book. The study was sponsored by the National Cancer Institute (NCI) at the National Institute of Health (NIH), the National Science Foundation (NSF) and the National Institute of Biomedical Imaging and Bioengineering at the NIH in the US under a cooperative agreement with the World Technology Evaluation Center (WTEC).

 

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Contents

Introduction
1
Complexity and Information Cancer as a MultiScale Complex Adaptive System
5
Mimicking the Microenvironment
31
Cancer Cell Mechanics
49
Fluid Mechanics and Transport in Tumors
72
The Dynamics of Cell Motility
89
Devices and New Diagnostic Principles
111
Clinical Perspective
131
Appendix A Aphelion Study Panelists and Advisors
137
Appendix B Site Visit Reports  Europe
143
Appendix C Site Visit Reports  Asia
265
Appendix D Site Visit Reports  United Kingdom
365
Appendix E Site Visit Reports  Brazil
386
Appendix F Recent Conferences
397
WTEC Publications
401
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