Biochemical Engineering: A Textbook for Engineers, Chemists and BiologistsCompletely revised, updated, and enlarged, this second edition now contains a subchapter on biorecognition assays, plus a chapter on bioprocess control added by the new co-author Jun-ichi Horiuchi, who is one of the leading experts in the field. The central theme of the textbook remains the application of chemical engineering principles to biological processes in general, demonstrating how a chemical engineer would address and solve problems. To create a logical and clear structure, the book is divided into three parts. The first deals with the basic concepts and principles of chemical engineering and can be read by those students with no prior knowledge of chemical engineering. The second part focuses on process aspects, such as heat and mass transfer, bioreactors, and separation methods. Finally, the third section describes practical aspects, including medical device production, downstream operations, and fermenter engineering. More than 40 exemplary solved exercises facilitate understanding of the complex engineering background, while self-study is supported by the inclusion of over 80 exercises at the end of each chapter, which are supplemented by the corresponding solutions. An excellent, comprehensive introduction to the principles of biochemical engineering. |
Contents
Introduction | 3 |
Elements of Physical Transfer Processes | 13 |
Chemical and Biochemical Kinetics | 27 |
Cell Kinetics | 47 |
Mass Transfer | 73 |
Bioreactors | 97 |
Membrane Processes | 133 |
CellLiquid Separation and Cell Disruption | 145 |
Adsorption and Chromatography | 165 |
Practical Aspects in Bioengineering | 189 |
Instrumentation and Control of Bioprocesses | 217 |
Downstream Operations in Bioprocesses | 235 |
Medical Devices | 251 |
Conversion Factors for Units | 279 |
4 | 289 |
295 | |
Other editions - View all
Common terms and phrases
adsorbent adsorption aeration aerobic antibody batch bioartificial liver device Biochemical Engineering bioprocess bioreactor blood oxygenators broth bubble column calculated cell concentration Chem chemical chromatography cm³ constant correlations culture curve decrease density dialysate diameter diffusivity dimensionless driving potential elution enzyme Equation equilibrium estimated example fed-batch feed fermentation fermentor film coefficient filtrate flux flow rate fluid gas–liquid heat transfer hematocrit hemodialyzer hemoglobin hollow fibers impeller increase interface k₁ k₁a kcal kcal h¯¹ KGaA kidney kmol laminar liquid phase mass transfer coefficient medium microfiltration microorganisms min¯¹ mmHg mobile phase molecules obtained overall oxygen transfer packed partial pressure particles PID control process variable protein reactant reaction rate reactor resistance set-point shear rate shown in Figure solution specific growth rate sterilization stirred tanks stirrer substrate surface temperature tube turbulent urea values velocity viscosity volume Wiley-VCH Verlag