Capillary Electrophoresis - Mass Spectrometry (CE-MS): Principles and Applications
This monograph offers the reader a complete overview on both principles and applications of CE-MS. Starting with an introductory chapter on detection in CE, also related and more specialized techniques such as electrophoretic and chromatographic preconcentration are discussed. A special emphasis is put on CE-MS interfaces, which are described in detail. In a separate chapter, attention is paid to sheath-liquid interfacing. The developments and possibilities of microchip CE-MS are also described. Applications to all relevant areas are discussed in distinct chapters, each written by experts in the respective fields.
Besides applications in pharmaceutical analysis and bioanalysis, recent implementations in food science, forensic analysis, analysis of intact proteins, metabolomics and proteomics are highlighted. MS is a perfectly appropriate detection system for CE, as efficient separation is coupled to sensitive and selection detection. Moreover, MS can provide structure information on the separated compounds. CE-MS has now been developed into a strong hyphenated system complementary to LC-MS. This monograph is an unique source of knowledge for everyone dealing with and interested in CE-MS.
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Electrospray Ionization Interface Development for Capillary
Role Parameters and Optimization
Recent Developments of Microchip Capillary Electrophoresis Coupled
OnLine Electrophoretic Electrochromatographic
CEMS in Drug Analysis and Bioanalysis
CEMS for the analysis of intact proteins
CEMS in Food Analysis and Foodomics
CEMS in Forensic Sciences with Focus on Forensic Toxicology
CEMS in Metabolomics
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